Nogales Aitor, DeDiego Marta L
Center for Animal Health Research, INIA-CISA, 28130 Madrid, Spain.
Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, 28049 Madrid, Spain.
Pathogens. 2020 Mar 17;9(3):220. doi: 10.3390/pathogens9030220.
Influenza virus infections represent a serious public health problem causing contagious respiratory disease and substantial morbidity and mortality in humans, resulting in a considerable economic burden worldwide. Notably, the number of deaths due to influenza exceeds that of any other known pathogen. Moreover, influenza infections can differ in their intensity, from mild respiratory disease to pneumonia, which can lead to death. Articles in this Special Issue have addressed different aspects of influenza in human health, and the advances in influenza research leading to the development of better therapeutics and vaccination strategies, with a special focus on the study of factors associated with innate or adaptive immune responses to influenza vaccination and/or infection.
流感病毒感染是一个严重的公共卫生问题，可导致人类传染性呼吸道疾病以及大量发病和死亡，在全球造成相当大的经济负担。值得注意的是，流感导致的死亡人数超过任何其他已知病原体。此外，流感感染的严重程度各不相同，从轻度呼吸道疾病到肺炎，甚至可导致死亡。本期特刊中的文章探讨了流感在人类健康方面的不同层面，以及流感研究的进展如何推动更好的治疗方法和疫苗接种策略的发展，特别关注与流感疫苗接种和/或感染的固有或适应性免疫反应相关因素的研究。
