Associate Professor, Dept of Pulmonary Medicine, Govt Medical College & Hospital, Sector-32, Chandigarh, 160030, India.
Ex-Senior Resident, Dept of Pulmonary Medicine, Govt Medical College & Hospital, Sector-32, Chandigarh, 160030, India.
Indian J Tuberc. 2020 Jan;67(1):143-147. doi: 10.1016/j.ijtb.2019.02.018. Epub 2019 Mar 6.
Tuberculosis associated Immune reconstitution inflammatory syndrome (IRIS) in a HIV negative patient can present with a multitude of clinic-radiological presentations that are often confused with drug resistance/treatment failure. Being a diagnosis of exclusion, this clinical entity is often prone to under-diagnosis. We present a series of 5 patients who presented with varied but uncommon IRIS manifestations. High index of suspicion coupled with clinical reasoning and judicious use of phenotypic and genotypic culture methods helped in their timely detection and successful treatment.
肺结核相关免疫重建炎症综合征（IRIS）在 HIV 阴性患者中可能表现出多种临床-放射学表现，这些表现常常与耐药性/治疗失败相混淆。由于这是一种排除性诊断，因此这种临床病症通常容易被漏诊。我们介绍了一系列 5 例表现出不同但不常见的 IRIS 表现的患者。高度怀疑、临床推理以及明智地使用表型和基因型培养方法有助于及时发现并成功治疗。
