Department of Neurology, University Medical Centre Maribor, Ljubljanska 5, 2000, Maribor, Slovenia.
Faculty of Medicine, University of Maribor, Taborska ulica 8, 2000, Maribor, Slovenia.
Acta Neurol Belg. 2020 Jun;120(3):681-685. doi: 10.1007/s13760-020-01330-5. Epub 2020 Mar 19.
Vascular cognitive impairment (VCI) is a common feature of vascular brain lesions. The heterogeneity of clinical presentation after a stroke makes it challenging to find. However, the Montreal Cognitive Assessment Scale (MoCA) may be suitable for such purpose. Aim of the present study was to validate the Slovenian version of MoCA for detecting cognitive impairment after ischemic stroke. Seventy patients up to three months after ischemic stroke and 69 age-matched healthy control were included. All performed the MoCA and Hachinski Ischemic Scale (HIS). Cut-off value, sensitivity, specificity and likelihood ratio of MoCA were calculated with the receiver operating characteristic curve. Mean age of healthy controls was 67.1 (SD 9.2) years, mean MoCA was 25.8 (SD 2.6) points, and mean HIS was [1.9 (SD 1.5). There were no age differences between healthy controls and patients [70.4 (SD 10.9) years]. However, patients performed significantly worse on MoCA [mean 18.7 (SD 6.3) points) and had higher HIS score (7.6 (SD 0.3) points]. Optimal cut-off values for MoCA were 24/25 points. The area under the curve was 0.86, sensitivity was 81%, and specificity was 70%. A negative correlation was found between MoCA and education and age. Our results demonstrate that an optimal cut-off for screening for VCI in the Slovenian population is 24/25 points on MoCA, which is similar to other studies performed on patients with different cultural background. The test is easy to perform and could be used in daily clinical practice.
血管性认知障碍（VCI）是血管性脑损伤的常见特征。由于中风后的临床表现存在异质性，因此很难发现。然而，蒙特利尔认知评估量表（MoCA）可能适用于这种目的。本研究旨在验证 MoCA 的斯洛文尼亚版本，以检测缺血性中风后的认知障碍。纳入了 70 名缺血性中风后 3 个月内的患者和 69 名年龄匹配的健康对照者。所有患者均进行了 MoCA 和哈钦斯基缺血量表（HIS）评估。通过受试者工作特征曲线计算 MoCA 的截断值、敏感性、特异性和似然比。健康对照组的平均年龄为 67.1（9.2）岁，平均 MoCA 为 25.8（2.6）分，平均 HIS 为 1.9（1.5）分。健康对照组和患者之间的年龄无差异[70.4（10.9）岁]。然而，患者的 MoCA 评分明显较低[平均 18.7（6.3）分]，HIS 评分较高[7.6（0.3）分]。MoCA 的最佳截断值为 24/25 分。曲线下面积为 0.86，敏感性为 81%，特异性为 70%。MoCA 与教育和年龄呈负相关。我们的结果表明，在斯洛文尼亚人群中，用于筛查 VCI 的最佳截断值为 MoCA 的 24/25 分，与在不同文化背景的患者中进行的其他研究相似。该测试易于操作，可在日常临床实践中使用。
