Di Nicola Marco, Mazza Marianna, Panaccione Isabella, Moccia Lorenzo, Giuseppin Giulia, Marano Giuseppe, Grandinetti Paolo, Camardese Giovanni, De Berardis Domenico, Pompili Maurizio, Janiri Luigi
Department of Psychiatry, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Rome, Italy.
Institute of Psychiatry, Università Cattolica del Sacro Cuore, Rome, Italy.
Front Psychiatry. 2020 Mar 5;11:95. doi: 10.3389/fpsyt.2020.00095. eCollection 2020.
Climate and weather are known to affect multiple areas of human life, including mental health. In bipolar disorder (BD), seasonality represents an environmental trigger for mood switches, and climatic variables may contribute to recurrences. Several studies reported seasonal and climatic-related variations in the rate of suicide attempts. Suicide risk is relevant in BD, with approximately 25% of patients attempting suicide. Therefore, this study aimed to assess sensitivity to weather and climatic variations in BD subjects and its relationship with lifetime suicide attempts.
Three hundred fifty-two euthymic BD and 352 healthy control subjects, homogeneous with respect to socio-demographic characteristics, were enrolled. All participants were administered the METEO-Questionnaire (METEO-Q) to evaluate susceptibility to weather and climatic changes. We also investigated the potential relationship between sensitivity to climate and weather and lifetime suicide attempts in BD patients.
METEO-Q scores and the number of subjects reaching the cut-off for meteorosensitivity/meteoropathy were significantly higher in BD patients. Within the clinical group, BD subjects with lifetime suicide attempts obtained higher METEO-Q scores, with no differences between BD-I and BD-II. The number of suicide attempts directly correlated with METEO-Q scores. The presence of suicide attempts was associated with the physical and psychological symptoms related to weather variations.
Our findings support the relevance of sensitivity to weather and climate variations in a large sample of BD subjects and point out the association of this feature with lifetime suicide attempts.
众所周知，气候和天气会影响人类生活的多个领域，包括心理健康。在双相情感障碍（BD）中，季节性是情绪转换的环境触发因素，气候变量可能导致复发。多项研究报告了自杀未遂率的季节性和与气候相关的变化。自杀风险在双相情感障碍中很重要，约25%的患者曾试图自杀。因此，本研究旨在评估双相情感障碍患者对天气和气候变化的敏感性及其与终身自杀未遂的关系。
招募了352名心境正常的双相情感障碍患者和352名健康对照者，他们在社会人口统计学特征方面具有同质性。所有参与者都接受了气象问卷（METEO-Q），以评估对天气和气候变化的易感性。我们还研究了双相情感障碍患者对气候和天气的敏感性与终身自杀未遂之间的潜在关系。
双相情感障碍患者的METEO-Q评分以及达到气象敏感性/气象病临界值的受试者数量显著更高。在临床组中，有终身自杀未遂的双相情感障碍患者获得了更高的METEO-Q评分，双相I型和双相II型之间没有差异。自杀未遂次数与METEO-Q评分直接相关。自杀未遂的发生与天气变化相关的身体和心理症状有关。
我们的研究结果支持了在大量双相情感障碍患者样本中对天气和气候变化敏感性的相关性，并指出了这一特征与终身自杀未遂的关联。
