Department of Microbiology and Parasitology, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
Department of Medical Chemistry, Biochemistry and Clinical Chemistry, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
Int J Environ Health Res. 2022 Jan;32(1):141-154. doi: 10.1080/09603123.2020.1741519. Epub 2020 Mar 20.
Formation of biofilms allows bacterial cells to survive in adverse environments. Nontuberculous mycobacteria are ubiquitous in aqueous environments, where they adhere to surfaces and create a biofilm. This has led to the emergence of healthcare-associated infections and the use of biomaterials in medicine. Essential oils (EO) are substances of natural origin whose effect on microorganisms has been the subject of numerous studies. Here, we investigated the effect of EO on nontuberculous mycobacteria and their early and mature biofilm formation in sterilised tap water. The combination of EO and increasing ambient temperature showed a synergistic effect on the reduction of biofilm formation of and on a polystyrene surface. A significant antibiofilm effect of EO was also found at subinhibitory concentrations, suggesting a potential role for it as an alternative disinfectant of natural water.
生物膜的形成使细菌细胞能够在恶劣的环境中存活。非结核分枝杆菌广泛存在于水相环境中，它们在那里附着在表面并形成生物膜。这导致了与医疗保健相关的感染和生物材料在医学中的应用的出现。精油（EO）是天然来源的物质，其对微生物的影响已成为众多研究的主题。在这里，我们研究了 EO 对非结核分枝杆菌及其在消毒自来水早期和成熟生物膜形成中的作用。EO 与环境温度升高的组合对减少 和 在聚苯乙烯表面上的生物膜形成显示出协同作用。在亚抑菌浓度下也发现了 EO 的显著抗生物膜作用，这表明它可能作为天然水的替代消毒剂发挥作用。
