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主动屏蔽7T磁共振成像中主观报告的体验效应:一项大规模研究。

Subjectively Reported Effects Experienced in an Actively Shielded 7T MRI: A Large-Scale Study.

作者信息

Hansson Boel, Markenroth Bloch Karin, Owman Titti, Nilsson Markus, Lätt Jimmy, Olsrud Johan, Björkman-Burtscher Isabella M

机构信息

Department of Medical Imaging and Physiology, Skåne University Hospital, Lund, Sweden.

Department of Diagnostic Radiology, Clinical Sciences, Lund University, Lund, Sweden.

出版信息

J Magn Reson Imaging. 2020 Oct;52(4):1265-1276. doi: 10.1002/jmri.27139. Epub 2020 Mar 20.

DOI:10.1002/jmri.27139
PMID:32196818
Abstract

BACKGROUND

Ultrahigh-field (UHF) MRI advances towards clinical use. Patient compliance is generally high, but few large-scale studies have investigated the effects experienced in 7T MRI systems, especially considering peripheral nerve stimulation (PNS) and caregiving.

PURPOSE

To evaluate the quantity, the intensity, and subjective experiences from short-term effects, focusing on the levels of comfort and compliance of subjects.

STUDY TYPE

Prospective.

POPULATION

In all, 954 consecutive MRIs in 801 subjects for 3 years.

FIELD STRENGTH

7T.

ASSESSMENT

After the 7T examination, a questionnaire was used to collect data.

STATISTICAL TESTS

Descriptive statistics, Spearman's rank correlation, Mann-Whitney U-test, and t-test.

RESULTS

The majority (63%) of subjects agreed that the MRI experience was comfortable and 93% would be willing to undergo future 7T MRI as a patient (5% undecided) and 82% for research purposes (12% undecided). The most common short-term effects experienced were dizziness (81%), inconsistent movement (68%), PNS (63%), headache (40%), nausea (32%), metallic taste (12%), and light flashes (8%). Of the subjects who reported having PNS (n = 603), 44% experienced PNS as "not uncomfortable at all," 45% as "little or very little uncomfortable," and 11% as "moderate to very much uncomfortable." Scanner room temperature was experienced more comfortable before (78%) than during (58%) examinations, and the noise level was acceptable by 90% of subjects. Anxiety before the examination was reported by 43%. Patients differed from healthy volunteers regarding an experience of headache, metallic taste, dizziness, or anxiety. Room for improvement was pointed out after 117 examinations concerning given information (n = 73), communication and sound system (n = 35), or nursing care (n = 15).

DATA CONCLUSION

Subjectively reported effects occur in actively shielded 7T MRI and include physiological responses and individual psychological issues. Although leaving room for improvement, few subjects experienced these effects being so uncomfortable that they would lead to aversion to future UHF examinations.

LEVEL OF EVIDENCE

1 TECHNICAL EFFICACY: Stage 5 J. Magn. Reson. Imaging 2020;52:1265-1276.

摘要

背景

超高场(UHF)磁共振成像(MRI)正朝着临床应用发展。患者的依从性总体较高,但很少有大规模研究调查在7T MRI系统中所经历的影响,尤其是考虑到周围神经刺激(PNS)和护理情况。

目的

评估短期影响的数量、强度和主观体验,重点关注受试者的舒适度和依从性水平。

研究类型

前瞻性研究。

研究对象

801名受试者在3年中共进行了954次连续MRI检查。

场强

7T。

评估

在7T检查后,使用问卷收集数据。

统计检验

描述性统计、Spearman等级相关性分析、Mann-Whitney U检验和t检验。

结果

大多数(63%)受试者认为MRI体验舒适,93%的受试者愿意未来作为患者接受7T MRI检查(5%未决定),82%的受试者愿意为研究目的接受检查(12%未决定)。最常见的短期影响包括头晕(81%)、运动不一致(68%)、周围神经刺激(63%)、头痛(40%)、恶心(32%)、金属味(12%)和闪光(8%)。在报告有周围神经刺激的受试者(n = 603)中,44%的人认为周围神经刺激“一点也不难受”,45%的人认为“有点或非常轻微的难受”,11%的人认为“中度至非常难受”。与检查期间(58%)相比,更多受试者(78%)认为检查前扫描室温度更舒适,90%的受试者认为噪音水平可以接受。43%的受试者报告检查前有焦虑情绪。患者在头痛、金属味、头晕或焦虑体验方面与健康志愿者不同。在117次检查后指出了在提供信息(n = 73)、沟通和声音系统(n = 35)或护理(n = 15)方面有待改进之处。

数据结论

在主动屏蔽的7T MRI中会出现主观报告的影响,包括生理反应和个体心理问题。尽管仍有改进空间,但很少有受试者觉得这些影响非常不舒服以至于会导致他们厌恶未来的超高场检查。

证据水平

1 技术效能:5级 《磁共振成像杂志》2020年;52:1265 - 1276。

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