Friebe Björn, Wollrab Astrid, Thormann Markus, Fischbach Katharina, Ricke Jens, Grueschow Marcus, Kropf Siegfried, Fischbach Frank, Speck Oliver
Department of Radiology and Nuclear Medicine, Otto-von-Guericke University Magdeburg, Germany.
Department of Biomedical Magnetic Resonance (BMMR), Division Experimental Physics, Faculty of Physics, Otto-von-Guericke University Magdeburg, Germany.
J Magn Reson Imaging. 2015 Jun;41(6):1675-81. doi: 10.1002/jmri.24748. Epub 2014 Sep 19.
To determine the subjective experience of subjects undergoing 7T magnetic resonance imaging (MRI) compared to a mock scanner with no magnetic field.
In all, 44 healthy subjects were exposed to both the B0 field of a 7T whole-body MRI and a realistic mock scanner with no magnetic field. Subjects were blinded to the actual field strength and no scanning was performed. After exposure, subjects rated their experience of potential sensory perceptions.
The most frequently observed side effect was vertigo while entering the gantry, which was reported by 38.6% (n = 17). Other frequent side effects were the appearance of phosphenes (18.2%, n = 8), thermal heat sensation (15.9%), unsteady gait after exposure (13.6%, n = 6), and dizziness (13.6%). All side effects were reported significantly more often after 7T exposure. Nine subjects (20.5%) did not report any sensory perceptions at all, ie, neither in the 7T scanner nor in the mock scanner.
Light, acute, and transient sensory perceptions can occur in subjects undergoing ultrahighfield MRI, of which vertigo seems to be the most frequently reported. Possible psychological effects might contribute to the emergence of such sensory perceptions, as some subjects also reported them to appear in a realistic mock scanner with no magnetic field.
与无磁场的模拟扫描仪相比，确定接受7T磁共振成像（MRI）的受试者的主观体验。
总共44名健康受试者分别暴露于7T全身MRI的B0场和无磁场的逼真模拟扫描仪中。受试者对实际场强不知情，且未进行扫描。暴露后，受试者对其潜在感官知觉的体验进行评分。
最常观察到的副作用是进入检查床时出现眩晕，有38.6%（n = 17）的受试者报告了这一情况。其他常见副作用包括光幻视（18.2%，n = 8）、热感（15.9%）、暴露后步态不稳（13.6%，n = 6）和头晕（13.6%）。所有副作用在7T暴露后报告的频率明显更高。9名受试者（20.5%）根本没有报告任何感官知觉，即在7T扫描仪和模拟扫描仪中均未报告。
接受超高场MRI的受试者可能会出现轻微、急性和短暂的感官知觉，其中眩晕似乎是报告最多的。一些受试者还报告这些感官知觉也出现在无磁场的逼真模拟扫描仪中，因此可能的心理效应可能导致了此类感官知觉的出现。
