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强脉冲光:导致准分子激光原位角膜磨镶术后慢性干眼综合征。

Intense pulsed light: results in chronic dry eye syndrome after LASIK.

作者信息

Fuentes Páez G, Soler Tomas J R, Burillo S

机构信息

Centro Médico Teknon, Clínica Oftalnova, Barcelona, España.

Centro Médico Teknon, Clínica Oftalnova, Barcelona, España.

出版信息

Arch Soc Esp Oftalmol (Engl Ed). 2020 May;95(5):226-230. doi: 10.1016/j.oftal.2020.02.007. Epub 2020 Mar 18.

DOI:10.1016/j.oftal.2020.02.007
PMID:32197872
Abstract

A report is presented on the visual and clinical results from a retrospective case series of patients with chronic, evaporative, dry eye syndrome (DES), after refractive surgery, and treated with intense pulsed light treatment (IPL). Four sessions were performed, and the Ocular Surface Disease Index (OSDI) questionnaire was completed before initiating treatment and after the last session. Pre- and post-treatment data included: visual acuity (VA), refraction, clinical evaluation (DEWS severity grading, and Oxford corneal staining), and Orbscan topography. Twenty eyes were treated and the following data recorded: SchirmerI 14.7±5.6; 15.6±3.4mm, tear breakup time (TBUT) 3.4±1.6; 5.1±1.2s (P>.003), DEWS 3.4±0.5; 1.6±0.7 (P<.003), Oxford grade 0.8±0.77; 0.4±0.75 (P>.003), VA 0.67±0.26; 0.90±0.15 (P<.0001), best corrected VA 0.83±0.18; 0.92±0.14 (P>.003), spherical equivalent -0.31±0.6; -0.08±0.38D (P>.003), OSDI 34±16; 28±11.0 points (P>.003), frequency artificial tear use 3.4±2.0; 2.5±1.9 times/day (P>.03). A significant clinical and visual improvement was observed, together with a decreased frequency in artificial tear use, in LASIK patients with chronic DES after IPL treatment.

摘要

本文报告了一组接受屈光手术后患有慢性蒸发型干眼综合征(DES)并接受强脉冲光治疗(IPL)的患者的回顾性病例系列的视觉和临床结果。共进行了四个疗程,在开始治疗前和最后一个疗程后完成了眼表疾病指数(OSDI)问卷。治疗前后的数据包括:视力(VA)、屈光、临床评估(干眼严重程度分级和牛津角膜染色)以及Orbscan地形图。对20只眼睛进行了治疗,并记录了以下数据:泪液分泌试验I为14.7±5.6;15.6±3.4mm,泪膜破裂时间(TBUT)为3.4±1.6;5.1±1.2秒(P>.003),干眼严重程度分级为3.4±0.5;1.6±0.7(P<.003),牛津分级为0.8±0.77;0.4±0.75(P>.003),视力为0.67±0.26;变为0.90±0.15(P<.0001),最佳矫正视力为0.83±0.18;0.92±0.14(P>.003),等效球镜为-0.31±0.6;变为-0.08±0.38D(P>.003),OSDI为34±16;变为28±11.0分(P>.003),人工泪液使用频率为3.4±2.0;变为2.5±1.9次/天(P>.03)。在接受IPL治疗的慢性DES的LASIK患者中,观察到了显著的临床和视觉改善,同时人工泪液的使用频率降低。

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引用本文的文献

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Post-LASIK dry eye disease: A comprehensive review of management and current treatment options.准分子激光原位角膜磨镶术后干眼症:管理与当前治疗选择的综合综述
Front Med (Lausanne). 2023 Apr 11;10:1057685. doi: 10.3389/fmed.2023.1057685. eCollection 2023.
2
Characterization and Prediction of the Clinical Outcome of Intense Pulsed Light-Based Treatment in Dry Eye Associated to Meibomian Gland Dysfunction.睑板腺功能障碍相关性干眼的强脉冲光治疗临床结局的特征分析与预测
J Clin Med. 2021 Aug 13;10(16):3573. doi: 10.3390/jcm10163573.