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老年移位股骨颈骨折内固定与半髋关节置换术的成本效果分析。

Internal fixation versus hemiarthroplasty for displaced femoral neck fractures in the elderly: A cost-effectiveness analysis.

机构信息

Department of Orthopedics, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, China, 100045.

Department of Orthopedics and Traumatology, Beijing Jishuitan Hospital, China, 100035.

出版信息

Injury. 2020 Jun;51(6):1346-1351. doi: 10.1016/j.injury.2020.03.002. Epub 2020 Mar 2.

Abstract

BACKGROUND

There is little information on the cost and outcome of different treatments for femoral neck fractures. This study aimed to evaluate the cost-effectiveness of internal fixation compared with hemiarthroplasty (HA) for elderly patients with displaced femoral neck fractures.

MATERIALS AND METHODS

A total of 121 patients ≥ 65 years old were divided into internal fixation (n = 58) or HA group (n = 63). Clinical outcome was evaluated by the EuroQol 5 dimensions (EQ-5D) score at 3, 12, and 24 months. The total costs including medical and non-medical expense were collected through hospitalisation information, cost diaries, and telephone interviews. A cost-utility analysis of the total costs in combination with quality-adjusted life years (QALYs) calculated by EQ-5D and survival time was conducted. Results were expressed in incremental cost-effectiveness ratio (ICER).

RESULTS

The mean EQ-5D index score in the HA group were higher at the early follow-up (p<0.05). At 24 months there were no differences in EQ-5D between the 2 treatment groups (p>0.05). Over the 2-year period, patients treated with HA gained 0.09-0.10 more QALYs than those treated with internal fixation, while the mean total costs for internal fixation (CNY 55,676) were significantly lower than for HA (CNY 80,297) (P<0.001). ICER indicated that internal fixation may be more cost-effective than HA.

CONCLUSION

HA is associated with better outcome than internal fixation in the treatment of displaced femoral neck fractures in elderly patients. However, internal fixation may be more cost-effective because of less total cost.

摘要

背景

对于股骨颈骨折的不同治疗方法的成本和结果,相关信息较少。本研究旨在评估与人工髋关节置换术(HA)相比,内固定治疗老年移位股骨颈骨折的成本效益。

材料和方法

共纳入 121 名年龄≥65 岁的患者,分为内固定(n=58)或 HA 组(n=63)。通过 EuroQol 5 维度(EQ-5D)评分在 3、12 和 24 个月时评估临床结果。通过住院信息、费用日记和电话访谈收集包括医疗和非医疗费用在内的总费用。通过 EQ-5D 计算的总费用和生存时间结合质量调整生命年(QALYs)进行成本效用分析。结果表示为增量成本效益比(ICER)。

结果

HA 组的平均 EQ-5D 指数在早期随访时较高(p<0.05)。在 24 个月时,两组之间的 EQ-5D 没有差异(p>0.05)。在 2 年期间,HA 治疗的患者比内固定治疗的患者获得 0.09-0.10 个更多的 QALYs,而内固定治疗的总费用(CNY 55676)明显低于 HA 治疗(CNY 80297)(P<0.001)。ICER 表明,与 HA 相比,内固定可能更具成本效益。

结论

HA 治疗老年移位股骨颈骨折的效果优于内固定,但由于总费用较低,内固定可能更具成本效益。

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