针刺对脑缺血再灌注损伤诱导的氧化应激的影响。
Effect of Acupuncture on Oxidative Stress Induced by Cerebral Ischemia-Reperfusion Injury.
作者信息
Chen Chao-Hsien, Hsieh Ching-Liang
机构信息
Department of Chinese Medicine, China Medical University Hospital, Taichung 40447, Taiwan.
Chinese Medicine Research Center, China Medical University, Taichung 40402, Taiwan.
出版信息
Antioxidants (Basel). 2020 Mar 19;9(3):248. doi: 10.3390/antiox9030248.
In this article, we review how acupuncture regulates oxidative stress to prevent ischemia-reperfusion injury. We electronically searched databases, including PubMed, Clinical Key and the Cochrane Library, from their inception to November 2019 by using the following medical subject headings and keywords: acupuncture, ischemia-reperfusion injury, oxidative stress, reactive oxygen species, and antioxidants. We concluded that acupuncture is effective in treating oxidation after ischemia-reperfusion injury. In addition to increasing the activity of antioxidant enzymes and downregulating the generation of reactive oxygen species (ROS), acupuncture also repairs the DNA, lipids, and proteins attacked by ROS and mediates downstream of the ROS pathway to apoptosis.
在本文中，我们综述了针灸如何调节氧化应激以预防缺血再灌注损伤。我们通过电子方式检索了包括PubMed、Clinical Key和Cochrane图书馆在内的数据库，检索时间从各数据库创建至2019年11月，使用了以下医学主题词和关键词：针灸、缺血再灌注损伤、氧化应激、活性氧和抗氧化剂。我们得出结论，针灸在治疗缺血再灌注损伤后的氧化反应方面是有效的。除了增加抗氧化酶的活性和下调活性氧（ROS）的生成外，针灸还能修复受ROS攻击的DNA、脂质和蛋白质，并介导ROS途径下游至细胞凋亡。
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