生物打印策略用于分泌上皮类器官。
Bioprinting Strategies for Secretory Epithelial Organoids.
机构信息
Department of Preclinical and Applied Animal Science, Faculty of Veterinary Science, Mahidol University, Nakhon Pathom, Thailand.
Exocrine Gland Biology and Regeneration Research Group, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand.
出版信息
Methods Mol Biol. 2020;2140:243-249. doi: 10.1007/978-1-0716-0520-2_16.
Novel three-dimensional (3D) biofabrication platforms can allow magnetic 3D bioprinting (M3DB) by using magnetic nanoparticles to tag cells and then spatially arrange them in 3D around magnet dots. Here, we report an M3DB methodology to generate salivary gland-like epithelial organoids from stem cells. These organoids possess a neuronal network that responds to saliva neurostimulants.
新型三维（3D）生物制造平台可利用磁性纳米粒子标记细胞，然后在磁点周围的 3D 空间中对其进行空间排列，从而实现磁性 3D 生物打印（M3DB）。在这里，我们报告了一种从干细胞生成唾液腺样上皮类器官的 M3DB 方法。这些类器官拥有响应唾液神经刺激物的神经网络。
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