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微线圈和 Hookwire 术前定位技术的倾向性评分匹配比较研究。

Comparative study on preoperative localization techniques using microcoil and hookwire by propensity score matching.

机构信息

Department of Thoracic Surgery, Center for Mini-invasive Thoracic Surgery, People's Hospital, Peking University, Beijing, China.

Department of Thoracic Surgery, Shijitan Hospital, Beijing, China.

出版信息

Thorac Cancer. 2020 Jun;11(6):1386-1395. doi: 10.1111/1759-7714.13365. Epub 2020 Mar 24.

Abstract

BACKGROUND

The purpose of this study was to compare the efficacy and safety of two preoperative pulmonary nodule localization techniques using microcoil and hookwire.

METHODS

A total of 307 patients with 324 pulmonary nodules were included in the study from March 2012 to October 2016 in two medical centers. Baseline data, positioning operation data, success rate, complications, surgery and pathological results were statistically analyzed. Complications were used as the dependent variables, whereas others were used as covariates for the propensity score matching of the two groups. Statistical analyses were performed to compare the success rate and complication rate of the matched groups.

RESULTS

There were 218 lesions in the microcoil group and 106 nodules in the hookwire group. There were no significant differences in gender, age and the location of nodules between the two groups. The diameters of the nodules were smaller (8.2 ± 3.5 mm vs. 10.7 ± 4.3 mm) and solid nodules were fewer (11.5% vs. 26.4%) in the microcoil group. The complication rate of the two groups was not statistically significant. After propensity score matching, 71 patients in each group were successfully matched. We found that the success rate was higher (97.2% vs. 94.4%) and the incidence of complications was lower (31% vs. 15.5%) in the microcoil group.

CONCLUSIONS

Both techniques have been shown to be effective in preoperative localization of tiny pulmonary nodules. The method of microcoil localization has more advantages in clinical application.

KEY POINTS

Comparison of the efficacy and safety of two methods in preoperative pulmonary nodule localization in order to determine the optimal method.

摘要

背景

本研究旨在比较使用微线圈和 Hookwire 两种术前肺结节定位技术的疗效和安全性。

方法

本研究共纳入 2012 年 3 月至 2016 年 10 月在两个医疗中心的 307 例 324 个肺结节患者。对基线数据、定位操作数据、成功率、并发症、手术和病理结果进行统计学分析。并发症作为因变量,其他作为两组倾向评分匹配的协变量。对匹配组进行统计学分析,比较成功率和并发症发生率。

结果

微线圈组有 218 个病变,Hookwire 组有 106 个结节。两组在性别、年龄和结节位置方面无显著性差异。微线圈组结节直径较小(8.2±3.5mm 比 10.7±4.3mm),实性结节较少(11.5%比 26.4%)。两组并发症发生率无统计学意义。经倾向评分匹配后,每组各有 71 例患者成功匹配。我们发现微线圈组的成功率更高(97.2%比 94.4%),并发症发生率更低(31%比 15.5%)。

结论

两种技术均能有效定位微小肺结节。微线圈定位方法在临床应用中有更多优势。

重点

比较两种方法在术前肺结节定位中的疗效和安全性,以确定最佳方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2564/7262885/eb860d05a356/TCA-11-1386-g001.jpg

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