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基于市场篮分析的农药暴露鉴定,适用于累积饮食风险评估和食品监测计划。

Identification of a pesticide exposure based market basket suitable for cumulative dietary risk assessments and food monitoring programmes.

机构信息

Department Pesticides Safety, German Federal Institute for Risk Assessment (BfR) , Berlin, Germany.

出版信息

Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2020 Jun;37(6):989-1003. doi: 10.1080/19440049.2020.1737334. Epub 2020 Mar 24.

DOI:10.1080/19440049.2020.1737334
PMID:32207371
Abstract

Consideration of cumulative dietary risks is a requirement in the European legislation for setting maximum residue levels for pesticides. Current cumulative exposure assessment methodologies strongly rely on representative occurrence data from food monitoring programmes. This study provides a sensitivity analysis, utilising (i) European consumption data expressed as raw agricultural commodity (RAC) equivalents from 23 different countries as published by the European Food Safety Authority and (ii) all maximum residue levels established for pesticides under European Regulation (EC) No 396/2005. Based on two different degrees of conservatism, market baskets consisting of 16 or 41 RACs, respectively, were identified, covering the majority of the total chronic and acute daily exposure. The coverage of the exposure by these market baskets was tested by comparison of cumulative probabilistic exposure assessments for the German population using all food commodities and those using the reduced sets. It was demonstrated that ≥85% of the total chronic exposure is already covered by 16 RACs, while 41 RACs are required to reach a similarly satisfying coverage of the total acute exposure. Results from this study support resource efficient modelling of complex cumulative assessment scenarios and may help to improve the design of food monitoring programmes with respect to a more efficient assessment of potential consumer risks.

摘要

考虑累积膳食风险是欧洲立法机构为设定农药最大残留限量(MRLs)所必需的。目前的累积暴露评估方法主要依赖于食品监测计划中的代表性发生数据。本研究利用(i)欧洲食品安全局(EFSA)公布的来自 23 个不同国家的原始农业商品(RAC)当量的欧洲消费数据,以及(ii)根据欧洲法规(EC)No 396/2005 为农药设定的所有最大残留限量(MRLs),进行了敏感性分析。基于两种不同程度的保守性,分别确定了由 16 或 41 个 RAC 组成的市场篮子,涵盖了大部分慢性和急性每日总暴露量。通过比较使用所有食品商品和使用简化集的德国人口的累积概率暴露评估,测试了这些市场篮子对暴露的覆盖情况。结果表明,16 个 RAC 已经覆盖了 85%以上的总慢性暴露量,而要达到总急性暴露量的类似满意覆盖范围,则需要 41 个 RAC。本研究的结果支持对复杂的累积评估情景进行资源高效建模,并有助于改进食品监测计划的设计,以更有效地评估潜在的消费者风险。

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