Department of Nursing, Faculty of Health Sciences, Bartın University, Bartın, Turkey.
Int Wound J. 2020 Jun;17(3):831-841. doi: 10.1111/iwj.13344. Epub 2020 Mar 24.
This research was carried out with the aim of comparing the effects of platelet-rich plasma (PRP) gel and gas dressing with serum physiologic applied to stage II pressure ulcer in coccyx of patients for 2 months on healing process and dressing costs. This prospective randomised controlled experimental study was conducted with 60 patients hospitalised in the palliative care unit after surgery. The experimental group (n = 30) was dressed with platelet-rich plasma gel. The control group (n = 30) was treated with serum physiologic dressing. At the end of the 20th observation of the patients in the experimental group, it was found that the mean scores of area, exudate, and tissue type in pressure sores decreased statistically (P < .001). In the control group, no significant difference was found between the mean PUSH score at the end of the 20th observation (P > .05). The study showed that PRP gel had a positive effect on healing of stage II pressure ulcers with platelet-rich plasma gel dressings. In addition, when evaluated in the long term, it was concluded that platelet-rich plasma gel is easily accessible and less costly than serum physiological dressing.
本研究旨在比较富血小板血浆(PRP)凝胶和血清生理气性敷料在 2 个月内治疗Ⅱ期尾骨压疮患者的效果,评估其对愈合过程和敷料费用的影响。这是一项前瞻性随机对照实验研究,纳入了 60 名手术后入住姑息治疗病房的患者。实验组(n = 30)采用富血小板血浆凝胶治疗,对照组(n = 30)采用血清生理敷料治疗。在第 20 次观察结束时,实验组患者的压疮面积、渗出物和组织类型评分均有显著下降(P <.001)。对照组患者在第 20 次观察结束时的 PUSH 评分平均值无显著差异(P >.05)。研究表明,PRP 凝胶对Ⅱ期压疮的愈合有积极作用,富血小板血浆凝胶敷料的应用可促进愈合。此外,从长期来看,PRP 凝胶易于获得,成本低于血清生理敷料。