Shanghai Key Laboratory of Advanced Polymeric Materials, Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai 200237, China.
Chem Rev. 2020 May 13;120(9):4111-4140. doi: 10.1021/acs.chemrev.9b00774. Epub 2020 Mar 26.
In recent years, the self-assembly of copolymer micelles has become an appealing frontier of supramolecular chemistry as a strategy to construct superstructures with multiple levels of complexity. The assembly of copolymer micelles is a form of higher-level self-assembly occurring at the nanoscale level where the building blocks are preassembled micelles. Compared to one-step hierarchical self-assembly, this assembly strategy is superior for manipulating multilevel architectures because the structures of the building blocks and higher-order hierarchies can be regulated separately in the first and higher-level assembly, respectively. However, despite the substantial advances in the self-assembly of copolymer micelles in recent years, universal laws have not been comprehensively summarized. This review article aims to provide an overview of the current progress and developing prospects of the self-assembly of copolymer micelles. In particular, the significant role of theoretical simulations in revealing the mechanism of copolymer micelle self-assembly is discussed.
近年来，作为构建具有多层次复杂性超结构的策略，共聚物胶束的自组装已成为超分子化学的一个热门前沿领域。共聚物胶束的组装是一种在纳米尺度水平上发生的高级别自组装形式，其中构建块是预先组装好的胶束。与一步法的分级自组装相比，这种组装策略更有利于操控多层次结构，因为在第一级和更高一级的组装中，可以分别对构建块和更高阶层次的结构进行调节。然而，尽管近年来共聚物胶束的自组装取得了实质性的进展，但尚未全面总结出通用规律。本文旨在综述共聚物胶束自组装的最新进展和发展前景。特别地，讨论了理论模拟在揭示共聚物胶束自组装机制方面的重要作用。
