Geriatric department, Hospital de Sant Jaume i Santa Magdalena, Consorci Sanitari del Maresme, 08304 Mataro, Spain.
Gastrointestinal Physiology Laboratory. CIBERehd CSdM-UAB, Hospital de Mataró, 08404 Mataro, Spain.
Nutrients. 2020 Mar 24;12(3):863. doi: 10.3390/nu12030863.
The prevalence of older patients with dementia and oropharyngeal dysphagia (OD) is rising and management is poor. Our aim was to assess the prevalence, risk factors, and long-term nutritional and respiratory complications during follow-up of OD in older demented patients. We designed a prospective longitudinal quasi-experimental study with 255 patients with dementia. OD was assessed with the Volume-Viscosity Swallowing Test and a geriatric evaluation was performed. OD patients received compensatory treatments based on fluid viscosity and texture modified foods and oral hygiene, and were followed up for 18 months after discharge. Mean age was 83.5 ± 8.0 years and Alzheimer's disease was the main cause of dementia (52.9%). The prevalence of OD was 85.9%. Up to 82.7% patients with OD required fluid thickening and 93.6% texture modification, with poor compliance. OD patients were older ( < 0.007), had worse functionality ( < 0.0001), poorer nutritional status ( = 0.014), and higher severity of dementia ( < 0.001) than those without OD and showed higher rates of respiratory infections ( = 0.011) and mortality ( = 0.0002) after 18 months follow-up. These results show that OD is very prevalent among patients with dementia and is associated with impaired functionality, malnutrition, respiratory infections, and increased mortality. New nutritional strategies should be developed to increase the compliance and therapeutic effects for this growing population of dysphagic patients.
痴呆和口咽性吞咽困难(OD)老年患者的患病率不断上升,但其管理水平较差。我们的目的是评估老年痴呆症患者 OD 随访期间的患病率、风险因素以及长期营养和呼吸并发症。我们设计了一项前瞻性纵向准实验研究,纳入了 255 例痴呆症患者。使用容积粘度吞咽测试(Volume-Viscosity Swallowing Test)评估 OD,并进行老年综合评估。OD 患者接受基于液体粘度和质地改良食物的补偿性治疗以及口腔卫生,并在出院后随访 18 个月。患者平均年龄为 83.5 ± 8.0 岁,阿尔茨海默病是痴呆的主要病因(52.9%)。OD 的患病率为 85.9%。高达 82.7%的 OD 患者需要液体增稠,93.6%需要质地改良,但顺应性较差。与无 OD 的患者相比,OD 患者年龄更大(<0.007)、功能更差(<0.0001)、营养状况更差(=0.014)、痴呆症严重程度更高(<0.001),且在 18 个月随访期间,呼吸道感染(=0.011)和死亡率(=0.0002)更高。这些结果表明,OD 在痴呆症患者中非常普遍,与功能障碍、营养不良、呼吸道感染和死亡率增加有关。应该开发新的营养策略,以提高这一不断增长的吞咽困难患者群体的顺应性和治疗效果。