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比较营养筛查工具,以评估营养风险并预测墨西哥消化疾病患者的临床结局。

Comparison of nutritional screening tools to assess nutritional risk and predict clinical outcomes in Mexican patients with digestive diseases.

机构信息

Departamento de Clínicas de la Reproducción Humana, Crecimiento y Desarrollo Infantil, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, 44340, Guadalajara, Jalisco, Mexico.

Department of Welfare and Sustainable Development, University Center of the North, University of Guadalajara, 46200, Colotlan, Jalisco, Mexico.

出版信息

BMC Gastroenterol. 2020 Mar 26;20(1):79. doi: 10.1186/s12876-020-01214-1.

Abstract

BACKGROUND

The prevalence of malnutrition remains high in hospitals but no "gold standard" has been established to identify nutritional risks adequately. The Nutrition Risk Screening-2002 (NRS-2002), Subjective Global Assessment (SGA), and Controlling Nutritional Status Index (CONUT) are widely used screening tools, but their efficacy has not yet been compared in Mexican patients. Here, we aimed to compare the efficacy of these tools in identifying nutritional risks within the first 48 h of admission in a group of patients with gastrointestinal diseases.

METHODS

This was a cross-sectional study of 196 patients. The results of the screening tools, length of hospital stay, serum albumin and cholesterol concentrations, lymphocyte counts, age, body mass index (BMI), complications, and mortality were analyzed. Kappa (κ) statistics were applied to determine the degree of agreement between tools. The performances of the screening tools in predicting complications and mortality were assessed using binary logistic regression.

RESULTS

The NRS-2002, SGA, and CONUT tools identified nutritional risk in 67, 74, and 51% of the patients, respectively. The observed agreements between tools were: NRS2002/SGA, κ = 0.53; CONUT/NRS-2002, κ = 0.42; and SGA/CONUT, κ = 0.36. Within age groups, the best agreement was found in those aged 51-65 years (κ = 0.68). CONUT and length of stay were both predictive for the number of complications. The number of complications and serum cholesterol concentrations were predictive for mortality.

CONCLUSIONS

The proportion of patients identified as having nutritional risk was high using all three screening tools. SGA, NRS-2002, and CONUT had similar capacities for screening risk, but the best agreement was observed between NRS-2002 and SGA. Only CONUT predicted complications, but none of these tools performed well in predicting mortality.

摘要

背景

医院的营养不良患病率仍然很高,但尚未建立识别营养风险的“金标准”。营养风险筛查 2002(NRS-2002)、主观全面评估(SGA)和控制营养状态指数(CONUT)是广泛使用的筛查工具,但它们在墨西哥患者中的功效尚未得到比较。在这里,我们旨在比较这些工具在识别一组胃肠道疾病患者入院后 48 小时内的营养风险的功效。

方法

这是一项对 196 名患者的横断面研究。分析了筛查工具的结果、住院时间、血清白蛋白和胆固醇浓度、淋巴细胞计数、年龄、体重指数(BMI)、并发症和死亡率。应用 Kappa(κ)统计来确定工具之间的一致性程度。使用二项逻辑回归评估筛查工具在预测并发症和死亡率方面的性能。

结果

NRS-2002、SGA 和 CONUT 工具分别在 67%、74%和 51%的患者中识别出营养风险。工具之间的观察一致性为:NRS2002/SGA,κ=0.53;CONUT/NRS-2002,κ=0.42;SGA/CONUT,κ=0.36。在年龄组内,发现年龄在 51-65 岁之间的患者具有最佳的一致性(κ=0.68)。CONUT 和住院时间都与并发症的数量相关。并发症的数量和血清胆固醇浓度与死亡率相关。

结论

使用所有三种筛查工具,都发现患者被识别为存在营养风险的比例很高。SGA、NRS-2002 和 CONUT 筛查风险的能力相似,但 NRS-2002 和 SGA 之间的一致性最好。只有 CONUT 预测并发症,但这些工具在预测死亡率方面都表现不佳。

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