School of Food and Biological Engineering, Jiangsu University, Zhenjiang, Jiangsu Province 212013, China.
University of Natural Resources and Life Sciences, Vienna, Austria; Department of Agrobiotechnology, Institute of Environmental Biotechnology, Konrad Lorenz Straße 20, 3430 Tulln, Austria.
Bioresour Technol. 2020 Jun;306:123132. doi: 10.1016/j.biortech.2020.123132. Epub 2020 Mar 12.
Polyhydroxyalkanoates (PHAs) are inevitably a key biopolymer that has the potential to replace the conventional petrochemical based plastics that pose jeopardy to the environment globally. Even then the reach of PHA in the common market is so restricted. The economy of PHA is such that, even after several attempts the overall production cost seems to be high and this very factor surpasses PHAs usage when compared to the conventional polymers. The major focus of the review relies on the synthesis of PHA from Mixed Microbial Cultures (MMCs), through a 3-stage process most probably utilizing feedstocks from waste streams or models that mimic them. Emphasis was given to the works carried out in the past decade and their coherence with each and every individual criteria (Aeration, Substrate and bioprocess parameters) such that to understand their effect in enhancing the overall production of PHA.
聚羟基烷酸酯（PHA）是一种不可避免的关键生物聚合物，它有可能取代对全球环境构成威胁的传统基于石油的塑料。即便如此，PHA 在普通市场上的应用也受到了极大的限制。PHA 的经济性使得，即使经过多次尝试，总体生产成本似乎仍然很高，这一因素使得 PHA 的使用超过了传统聚合物。综述的主要重点是通过可能利用来自废物流的原料或模拟它们的模型的 3 阶段过程，从混合微生物培养物（MMC）中合成 PHA。重点介绍了过去十年所进行的工作及其与每一个单独标准（曝气、底物和生物过程参数）的一致性，以便了解它们在提高 PHA 总产量方面的作用。
