Center for Alzheimer's Disease and Related Disorders, Institute of Psychiatry, 28125Universidade Federal do Rio de Janeiro, Brazil.
Department of Political Sociology, Universidade Federal de Santa Catarina, Brazil.
J Geriatr Psychiatry Neurol. 2021 Mar;34(2):119-127. doi: 10.1177/0891988720915521. Epub 2020 Mar 30.
The quality of life (QoL) of people with Alzheimer disease (PwAD) may be influenced by the type of relationship between carer and the PwAD. Dyads of 98 PwAD/carers (N = 49 spouse-carers; N = 49 nonspouses carers) were measured about QoL, cognition, dementia severity, awareness of disease, functionality, depression, anxiety, and burden of care. Univariate and multivariate regression analyses were conducted to identify the factors that influenced the spouse and nonspouse self-report PwAD QoL (PQOL) and to compare carers' ratings of PwAD QoL (C-PQOL). The total score of QoL for spouse and nonspouse PwAD showed no significant difference ( = .29). The linear regression demonstrated that higher awareness of disease was significantly related to spouse PQOL ( = .001). Nonspouse PQOL was negatively related to lower depression ( = .007). The total score of QoL for spouse and nonspouse C-PQOL showed no significant difference ( = .14). The linear regression demonstrated that depression of spouse-PwAD ( < .001) and burden of care ( = .001) were negatively related to spouse-dyads' C-PQOL. The nonspouse-dyads C-PQOL was negatively related to depression of nonspouse-PwAD ( < .001), awareness of disease ( = .001), and the mood of the carer ( = .01). Spouse and nonspouse PwAD evaluate PQOL better than carers (C-PQOL). No significant difference was found in the total PQOL and C-PQOL of spouse and nonspouse, but dyads evaluated differently about what is important to assess QoL.
阿尔茨海默病患者(PwAD)的生活质量(QoL)可能受到照顾者与 PwAD 之间关系类型的影响。对 98 对 PwAD/照顾者(N=49 对配偶照顾者;N=49 对非配偶照顾者)进行了 QoL、认知、痴呆严重程度、疾病意识、功能、抑郁、焦虑和照顾负担的测量。进行了单变量和多变量回归分析,以确定影响配偶和非配偶自我报告 PwAD QoL(PQOL)的因素,并比较照顾者对 PwAD QoL(C-PQOL)的评价。配偶和非配偶 PwAD 的 QoL 总分无显著差异(t=0.29)。线性回归表明,更高的疾病意识与配偶 PQOL 显著相关(β=0.001)。非配偶 PQOL 与较低的抑郁呈负相关(β=0.007)。配偶和非配偶 C-PQOL 的 QoL 总分无显著差异(t=0.14)。线性回归表明,配偶-PwAD 的抑郁(<0.001)和照顾负担(=0.001)与配偶对 C-PQOL 呈负相关。非配偶对 C-PQOL 与非配偶对 PwAD 的抑郁(<0.001)、疾病意识(=0.001)和照顾者的情绪(=0.01)呈负相关。配偶和非配偶 PwAD 对 PQOL 的评价优于照顾者(C-PQOL)。配偶和非配偶的 PQOL 和 C-PQOL 总分无显著差异,但对评估 QoL 重要性的评价不同。