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J Int Med Res. 2020 Mar;48(3):300060520905438. doi: 10.1177/0300060520905438.
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The VAC regimen for adult rhabdomyosarcoma: Differences between adolescent/young adult and older patients.成人横纹肌肉瘤的VAC方案:青少年/青年患者与老年患者之间的差异。
Asia Pac J Clin Oncol. 2020 Apr;16(2):e47-e52. doi: 10.1111/ajco.13279. Epub 2019 Oct 28.
2
Rhabdomyosarcoma: Advances in Molecular and Cellular Biology.横纹肌肉瘤:分子与细胞生物学进展
Sarcoma. 2015;2015:232010. doi: 10.1155/2015/232010. Epub 2015 Sep 1.
3
The inconvenience of convenience cohorts: rhabdomyosarcoma and the PAX-FOXO1 biomarker.便利队列的不便之处:横纹肌肉瘤和 PAX-FOXO1 生物标志物。
Cancer Epidemiol Biomarkers Prev. 2012 Jul;21(7):1012-8. doi: 10.1158/1055-9965.EPI-12-0207. Epub 2012 May 7.
4
Prognostic significance and tumor biology of regional lymph node disease in patients with rhabdomyosarcoma: a report from the Children's Oncology Group.横纹肌肉瘤患者区域淋巴结疾病的预后意义和肿瘤生物学:来自儿童肿瘤学组的报告。
J Clin Oncol. 2011 Apr 1;29(10):1304-11. doi: 10.1200/JCO.2010.29.4611. Epub 2011 Feb 28.
5
Long-term survivors of adult rhabdomyosarcoma of maxillary sinus following multimodal therapy: case reports and literature reviews.多模式治疗后上颌窦成人横纹肌肉瘤长期存活者:病例报告与文献综述
Chang Gung Med J. 2010 Jul-Aug;33(4):466-71.
6
Alveolar rhabdomyosarcoma of vulva.外阴肺泡状横纹肌肉瘤
Indian J Pathol Microbiol. 2010 Jan-Mar;53(1):167-8. doi: 10.4103/0377-4929.59218.
7
Comparing adult and pediatric rhabdomyosarcoma in the surveillance, epidemiology and end results program, 1973 to 2005: an analysis of 2,600 patients.1973年至2005年监测、流行病学和最终结果计划中成人与儿童横纹肌肉瘤的比较:2600例患者的分析
J Clin Oncol. 2009 Jul 10;27(20):3391-7. doi: 10.1200/JCO.2008.19.7483. Epub 2009 Apr 27.
8
The Intergroup Rhabdomyosarcoma Study Group (IRSG): Major Lessons From the IRS-I Through IRS-IV Studies as Background for the Current IRS-V Treatment Protocols.横纹肌肉瘤协作组(IRSG):从IRS-I至IRS-IV研究中获得的主要经验教训,作为当前IRS-V治疗方案的背景依据
Sarcoma. 2001;5(1):9-15. doi: 10.1080/13577140120048890.
9
Clinicopathologic features of rhabdomyosarcoma of gynecologic origin in adults.成人妇科来源横纹肌肉瘤的临床病理特征
Am J Surg Pathol. 2007 Mar;31(3):382-9. doi: 10.1097/01.pas.0000213352.87885.75.
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Primary and metastatic rhabdomyosarcoma in the breast: report of two pediatric cases.乳腺原发性及转移性横纹肌肉瘤:两例儿科病例报告
Eur J Radiol. 2003 Dec;48(3):282-4. doi: 10.1016/s0720-048x(03)00041-x.

成人外阴横纹肌肉瘤:病例报告及文献复习。

Alveolar rhabdomyosarcoma of the vulva in an adult: a case report and literature review.

机构信息

Gynecology Department, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.

出版信息

J Int Med Res. 2020 Mar;48(3):300060520905438. doi: 10.1177/0300060520905438.

DOI:10.1177/0300060520905438
PMID:32223663
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7133084/
Abstract

Rhabdomyosarcoma (RMS) is a common soft tissue tumor in children, but it is rare in adults. Alveolar rhabdomyosarcoma (ARMS) is a subtype of RMS and is extremely rare in adults, especially concerning the genital tract. We report a case of a 20-year-old woman who was admitted to and treated in our hospital for an RMS of the vulva. The patient presented with local recurrence and bone metastasis during chemotherapy after surgery and died within 1 year of diagnosis. Based on a literature review, the prognosis of ARMS in adults is poor. The treatment strategy for ARMS is not well established yet. The lungs and bone are two common sites of metastasis of ARMS.

摘要

横纹肌肉瘤(RMS)是儿童常见的软组织肿瘤,但在成人中很少见。腺泡状横纹肌肉瘤(ARMS)是 RMS 的一种亚型,在成人中极为罕见,特别是在生殖道。我们报告了一例 20 岁女性,因外阴 RMS 在我院住院治疗。该患者在手术后化疗期间出现局部复发和骨转移,并在诊断后 1 年内死亡。基于文献回顾,成人 ARMS 的预后较差。ARMS 的治疗策略尚未确定。肺和骨是 ARMS 常见的转移部位。