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一例并发脑积水和脑室内出血的脑膜炎病例:治疗选择与结果综述

A case of meningitis complicated by Hydrocephalus and Intraventricular hemorrhage: A review of treatment options and outcomes.

作者信息

Gerstein Shawn, Gautam-Goyal Pranisha, Goyal Sameer

机构信息

North Shore University Hospital, Department of Infectious Diseases, 400 Community Drive, Manhasset, NY, 11030, United States.

North Shore University Hospital, Department of Infectious Diseases, 300 Community Drive, Manhasset, NY, 11030, United States.

出版信息

IDCases. 2020 Jan 18;19:e00704. doi: 10.1016/j.idcr.2020.e00704. eCollection 2020.

DOI:10.1016/j.idcr.2020.e00704
PMID:32226767
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7093742/
Abstract

is a gram-positive bacillus known to cause various human infections including central nervous system infections. The most common central nervous system manifestations are meningitis and rhomboencephalitis, however rare complications including hydrocephalus and intracerebral hemorrhage can occur and are associated with increased mortality and incidence of lasting neurologic sequelae. The mortality ranges from 17 % to greater than 30 % in patients with neurological involvement [[1], [2], [3]]. Various case reports have studied the differing treatment approaches and outcomes of patients who experienced these complications, and there is still no consensus on optimal treatment approaches. In this paper, we report a case of Listeria meningitis complicated by both acute hydrocephalus and intracerebral hemorrhage and analyze the factors that led to a favorable outcome by reviewing the existing literature.

摘要

是一种革兰氏阳性杆菌,已知可引起包括中枢神经系统感染在内的各种人类感染。最常见的中枢神经系统表现是脑膜炎和菱形脑炎,然而,罕见的并发症包括脑积水和脑出血也可能发生,并且与死亡率增加和持久神经后遗症的发生率相关。神经受累患者的死亡率在17%至超过30%之间[[1], [2], [3]]。各种病例报告研究了经历这些并发症的患者的不同治疗方法和结果,并且在最佳治疗方法上仍然没有共识。在本文中,我们报告了一例并发急性脑积水和脑出血的李斯特菌脑膜炎病例,并通过回顾现有文献分析了导致良好结果的因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/793b/7093742/191d08bb08f7/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/793b/7093742/9f5bfd87a700/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/793b/7093742/191d08bb08f7/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/793b/7093742/9f5bfd87a700/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/793b/7093742/191d08bb08f7/gr2.jpg

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本文引用的文献

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2
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IDCases. 2018 Sep 5;14:e00455. doi: 10.1016/j.idcr.2018.e00455. eCollection 2018.
3
Intra-cerebrospinal fluid antibiotics to treat central nervous system infections: A review and update.
脑室内注射抗生素治疗中枢神经系统感染:综述与更新
Clin Neurol Neurosurg. 2018 Jul;170:140-158. doi: 10.1016/j.clineuro.2018.05.007. Epub 2018 May 17.
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Clinical features and prognostic factors of listeriosis: the MONALISA national prospective cohort study.李斯特菌病的临床特征和预后因素:MONALISA 全国前瞻性队列研究。
Lancet Infect Dis. 2017 May;17(5):510-519. doi: 10.1016/S1473-3099(16)30521-7. Epub 2017 Jan 28.
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