Nachmias B, Orenbuch-Harroch E, Makranz C, Nechusthan H, Eliahou R, Ben-Yehuda D, Lossos A
Hadassah-Hebrew University Medical Center, Department of Hematology, Jerusalem, Israel.
Hadassah-Hebrew University Medical Center, Department of Infectious disease, Jerusalem, Israel.
IDCases. 2018 Sep 5;14:e00455. doi: 10.1016/j.idcr.2018.e00455. eCollection 2018.
is a gram-positive bacterium with a predilection to infect the central nervous system, often affecting immunocompromised or elderly patients. The most common manifestations are meningitis and rhomboencephalitis. We report two cases of Listeria meningitis complicated by acute hydrocephalus several days after presentation and we further review the literature of similar cases. We conclude that acute hydrocephalus is a significant, not often recognized, complication of Listeria meningitis, usually occurring several days from onset when coverage did not include anti-Listeria antimicrobials. In high risk patients, meningitis combined with acute hydrocephalus is suggestive of LM infection.
是一种革兰氏阳性菌，易感染中枢神经系统，常影响免疫功能低下或老年患者。最常见的表现是脑膜炎和菱形脑炎。我们报告了两例李斯特菌脑膜炎患者，在发病几天后并发急性脑积水，并进一步回顾了类似病例的文献。我们得出结论，急性脑积水是李斯特菌脑膜炎的一种重要但常未被认识到的并发症，通常在发病几天后出现，此时的治疗方案未包括抗李斯特菌抗菌药物。在高危患者中，脑膜炎合并急性脑积水提示李斯特菌感染。
