Department of Dermatology, KU Leuven, Leuven, Belgium.
Department of Dermatology, UZ Gent, Gent, Belgium.
Skin Res Technol. 2020 Sep;26(5):708-712. doi: 10.1111/srt.12859. Epub 2020 Mar 29.
Dermoscopy has proven its value in the diagnosis of skin cancer and, therefore, is well established in daily dermatology practice. Up until now, analogue white light dermoscopy is the standard. Multispectral dermoscopy is based on illumination of the skin with narrowband light sources with different wavelengths. Each of these wavelengths is differently absorbed by skin chromophores, such as pigment or (de)oxygenated blood. Multispectral dermoscopy could be a way to enhance the visualization of vasculature and pigment. We illustrate possible additional information by such "skin parameter maps" in some cases of basal cell carcinoma and Bowen's disease.
Using a new digital multispectral dermatoscope, skin images at multiple wavelengths are collected from different types of skin lesions. These particular images together with the knowledge on skin absorption properties, result in so called "skin parameter maps".
A "pigment contrast map," which shows the relative concentration of primarily pigment, and a "blood contrast map" which shows the relative concentration of primarily blood were created. Especially, the latter is of importance in diagnosing keratinocyte skin cancer hence vascular structures are a characteristic feature, as further illustrated in the study.
Skin parameter maps based on multispectral images can give better insight in the inner structures of lesions, especially in lesions with characteristic blood vessels such as Bowen's disease and basal cell carcinoma. Skin parameter maps can be used complementary to regular dermoscopy and could potentially facilitate diagnosing skin lesions.
皮肤镜已被证明在皮肤癌的诊断中有其价值，因此在日常皮肤科实践中得到了很好的应用。到目前为止，模拟白光皮肤镜是标准的。多光谱皮肤镜基于用不同波长的窄带光源照射皮肤。这些波长中的每一个都被皮肤色素（如色素或（去）氧合血液）以不同的方式吸收。多光谱皮肤镜可以增强血管和色素的可视化。我们通过基底细胞癌和 Bowen 病等一些病例中的这些“皮肤参数图”说明了可能的其他信息。
使用新的数字多光谱皮肤镜，从不同类型的皮肤病变中采集多个波长的皮肤图像。这些特定的图像以及对皮肤吸收特性的了解，产生了所谓的“皮肤参数图”。
创建了一个“色素对比图”，显示主要色素的相对浓度，和一个“血液对比图”，显示主要血液的相对浓度。后者在诊断角质形成细胞皮肤癌方面尤为重要，因为血管结构是其特征性特征，研究中进一步说明了这一点。
基于多光谱图像的皮肤参数图可以更好地了解病变的内部结构，特别是在具有特征性血管的病变中，如 Bowen 病和基底细胞癌。皮肤参数图可以作为常规皮肤镜的补充，有可能有助于诊断皮肤病变。
