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城市中服务不足的西班牙裔/拉丁裔人群中可检测到尿砷形态:来自拉丁裔研究:营养和身体活动评估研究 (SOLNAS) 的一项初步研究。

Urinary Arsenic Species are Detectable in Urban Underserved Hispanic/Latino Populations: A Pilot Study from the Study of Latinos: Nutrition & Physical Activity Assessment Study (SOLNAS).

机构信息

Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA.

出版信息

Int J Environ Res Public Health. 2020 Mar 27;17(7):2247. doi: 10.3390/ijerph17072247.

Abstract

BACKGROUND

Hispanics/Latinos represent >15% of the United States (US) population and experience a high burden of cardiovascular disease (CVD) and diabetes. Dietary exposure, particularly to arsenic (As), may be associated with CVD and diabetes in Hispanics/Latinos. Rural populations in the US exposed to As in drinking water have increased risk of diabetes and CVD; however, little is known about the risk among urban populations with low As in water who are mostly exposed to As through food.

METHODS

To explore the levels of inorganic arsenic exposure (the sum of inorganic and methylated arsenic species in urine, ∑As, corrected by a residual-based method) in persons of Hispanic/Latino origin, we conducted a pilot study quantifying urinary arsenic levels among 45 participants in the Study of Latinos: Nutrition & Physical Activity Assessment Study (SOLNAS).

RESULTS

The median (interquartile range) of the urinary arsenic species (µg/L) were as follows: inorganic As 0.6 (0.4, 1.0), monomethylarsonic acid 1.2 (0.7, 1.9), dimethylarsinic acid 7.2 (4.3, 15.3), and ∑As 6.0 (4.3, 10.5).

CONCLUSIONS

This study adds to the existing evidence that harmful forms of arsenic are present in this group of Hispanics/Latinos.

摘要

背景

西班牙裔/拉丁裔占美国(美国)人口的>15%,心血管疾病(CVD)和糖尿病负担沉重。饮食暴露,特别是砷(As),可能与西班牙裔/拉丁裔的 CVD 和糖尿病有关。美国农村地区饮用水中砷暴露的人群患糖尿病和 CVD 的风险增加;然而,对于水中砷含量低的城市人群,通过食物接触砷的风险知之甚少。

方法

为了探索西班牙裔/拉丁裔人群的无机砷暴露水平(尿中无机砷和甲基化砷的总和,用基于残差的方法校正,∑As),我们对拉丁裔研究:营养与体育活动评估研究(SOLNAS)中的 45 名参与者进行了一项试点研究,定量测定了尿液中的砷水平。

结果

尿中砷种类(μg/L)的中位数(四分位距)如下:无机砷 0.6(0.4,1.0)、一甲基砷酸 1.2(0.7,1.9)、二甲基砷酸 7.2(4.3,15.3)和∑As 6.0(4.3,10.5)。

结论

这项研究增加了现有证据,表明有害形式的砷存在于这群西班牙裔/拉丁裔人群中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ff59/7178047/f2f0c66e69dc/ijerph-17-02247-g001.jpg

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