Food Saf (Tokyo). 2017 Mar 30;5(1):24-28. doi: 10.14252/foodsafetyfscj.2016033s. eCollection 2017 Mar.
The Food Safety Commission of Japan (FSCJ) conducted a risk assessment on antimicrobial-resistant bacteria arising from the use of colistin sulfate, which is used as a feed additive and veterinary medicinal products in the livestock. Both and were considered as potential antimicrobial-resistant bacteria to be selected under the use of colistin sulfate in the livestock. As only limited reports were available on the colistin-resistance in , FSCJ conducted a risk assessment focusing on as a hazard, on which the information was rather available. In the release assessment, the degree of possible selection of the hazard was evaluated as "Medium". Considering proper cooking of the livestock products, the degree of possible human exposure to the resistant bacteria via livestock products was evaluated as "Low". The degree of possible reduction or loss of clinical effectiveness was evaluated as "High" considering the current situation of colistin use in human medicine. From the above, the overall estimation of the risk was "Medium".
日本食品安全委员会（FSCJ）对硫酸黏菌素使用过程中产生的抗菌药物耐药菌进行了风险评估。硫酸黏菌素用作牲畜的饲料添加剂和兽药产品。在牲畜使用硫酸黏菌素的情况下，[此处原文缺失两种细菌名称]均被视为可能产生的潜在抗菌药物耐药菌。由于关于[此处原文缺失一种细菌名称]对黏菌素耐药性的报告有限，FSCJ以[此处原文缺失一种细菌名称]为重点进行了风险评估，因为关于它的信息较多。在释放评估中，该危害的可能选择程度被评估为“中等”。考虑到牲畜产品的适当烹饪，人类通过牲畜产品接触耐药菌的可能性程度被评估为“低”。考虑到目前人类医学中黏菌素的使用情况，临床有效性可能降低或丧失的程度被评估为“高”。综上所述，风险的总体评估为“中等”。
