Bleker O P, Oosting J, Hemrika D J
Department of Obstetrics and Gynecology, Onze Lieve Vrouwe Gasthuis, Amsterdam, Netherlands.
Acta Genet Med Gemellol (Roma). 1988;37(1):41-6. doi: 10.1017/s0001566000004244.
The birthweights and placental weights of 3000 singletons, 1500 twin pairs and 67 triplets are studied in relation to the gestational age. From 30-32 weeks onwards, newborns of twin- and triplet gestation show lower birthweight as compared to singleton newborns. Placental indices (placental weights related to birthweights) are about alike in singletons, twins and triplets. From about 24 weeks onwards placental weights of twin and triplet newborns are smaller as compared to those of singletons. Obviously, children in multiple gestations become growth retarded, preceded by and very likely due to poor early placental development (placental crowding of the uterus).
对3000名单胎、1500对双胞胎和67名三胞胎的出生体重及胎盘重量与胎龄的关系进行了研究。从30至32周起，双胎和三胎妊娠的新生儿出生体重低于单胎新生儿。单胎、双胎和三胎的胎盘指数（胎盘重量与出生体重的比值）大致相似。从约24周起，双胎和三胎新生儿的胎盘重量比单胎新生儿的小。显然，多胎妊娠的胎儿会出现生长迟缓，这很可能是由于早期胎盘发育不良（子宫内胎盘拥挤）所致，且生长迟缓先于胎盘发育不良出现。
