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具有比率依赖发生率和饱和治疗的传染病模型稳定性行为的研究。

A study on the stability behavior of an epidemic model with ratio-dependent incidence and saturated treatment.

机构信息

Department of Applied Mathematics, Delhi Technological University, Delhi, 110042, India.

Institute of System Studies and Analysis, DRDO, Metcalfe House, Delhi, 110054, India.

出版信息

Theory Biosci. 2020 Jun;139(2):225-234. doi: 10.1007/s12064-020-00314-6. Epub 2020 Mar 30.

Abstract

In the present article, the dynamics of a novel combination of ratio-dependent incidence rate and saturated treatment rate in susceptible-infected-recovered disease compartmental model has been presented. The ratio-dependent incidence rate has been incorporated into the model to monitor the situation when ratio of the number of infectives to that of the susceptibles is getting higher. The saturated treatment rate of the infected population has been considered as Holling type II functional, which explains the limitation in treatment availability. From the mathematical analysis of the model, two types of equilibria of the model have been obtained, which are named as disease-free equilibrium (DFE) and endemic equilibrium (EE). The local stability behavior of equilibria has been investigated by the basic reproduction number [Formula: see text], center manifold theory and Routh-Hurwitz criterion. It has been investigated that the DFE is locally asymptotically stable when [Formula: see text], and when [Formula: see text], the DFE exhibits either a forward bifurcation or a backward bifurcation under some conditions. The local stability behavior of the EE has also been analyzed, and some conditions are obtained for the same. Finally, some numerical computations have been performed in support of our theoretical results.

摘要

本文提出了一种新的具有比率相关感染率和饱和治疗率的易感染者-感染者-恢复者疾病房室模型的动力学。比率相关感染率被纳入模型中,以监测感染者与易感染者的比例越来越高的情况。感染人群的饱和治疗率被认为是 Holling 型 II 功能,这解释了治疗资源的局限性。通过对模型的数学分析,得到了两种模型平衡点,分别称为无病平衡点(DFE)和地方病平衡点(EE)。通过基本再生数 [Formula: see text]、中心流形理论和 Routh-Hurwitz 准则,研究了平衡点的局部稳定性行为。当 [Formula: see text]时,DFE 是局部渐近稳定的,当 [Formula: see text]时,在某些条件下,DFE 表现出前向分岔或后向分岔。还分析了 EE 的局部稳定性行为,并得到了一些相同的条件。最后,进行了一些数值计算来支持我们的理论结果。

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