Shimizu A, Kurachi M, Yamaguchi N, Torii H, Isaki K
Department of Neuropsychiatry, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Japan.
Acta Psychiatr Scand. 1988 Dec;78(6):716-9. doi: 10.1111/j.1600-0447.1988.tb06410.x.
The relation between age at onset of schizophrenia diagnosed using DSM-III criteria and the presence or absence of this illness among first-degree relatives was investigated in 2417 patients. The mean age at onset among those with a family history of schizophrenia was slightly and nonsignificantly earlier than that of schizophrenic patients without a positive family history. The former developed their illness before the age of 25 years more frequently than did the latter.
对2417名患者进行了研究，以探讨使用《精神疾病诊断与统计手册》第三版（DSM - III）标准诊断的精神分裂症发病年龄与一级亲属中是否患有该疾病之间的关系。有精神分裂症家族史的患者的平均发病年龄比无阳性家族史的精神分裂症患者略早，但无显著差异。前者在25岁之前发病的频率比后者更高。
