COVID-19: is the ACE2 just a foe?
作者信息
Jakovac Hrvoje
机构信息
Department of Physiology and Immunology, Medical Faculty, University of Rijeka, Rijeka, Croatia.
出版信息
Am J Physiol Lung Cell Mol Physiol. 2020 May 1;318(5):L1025-L1026. doi: 10.1152/ajplung.00119.2020. Epub 2020 Apr 1.
Abstract
摘要
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J Crohns Colitis. 2020 Sep 16;14(9):1334-1336. doi: 10.1093/ecco-jcc/jjaa061.
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Covid-19 infection and mortality: a physiologist's perspective enlightening clinical features and plausible interventional strategies.新型冠状病毒肺炎感染与死亡率：生理学家视角下的临床特征与可行干预策略解析
Am J Physiol Lung Cell Mol Physiol. 2020 May 1;318(5):L1020-L1022. doi: 10.1152/ajplung.00097.2020. Epub 2020 Mar 24.
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Soluble angiotensin-converting enzyme 2: a potential approach for coronavirus infection therapy?可溶性血管紧张素转化酶 2：冠状病毒感染治疗的潜在方法？
Clin Sci (Lond). 2020 Mar 13;134(5):543-545. doi: 10.1042/CS20200163.
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Evidence for Gastrointestinal Infection of SARS-CoV-2.新型冠状病毒2019（SARS-CoV-2）胃肠道感染的证据。
Gastroenterology. 2020 May;158(6):1831-1833.e3. doi: 10.1053/j.gastro.2020.02.055. Epub 2020 Mar 3.
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ACE2 exhibits protective effects against LPS-induced acute lung injury in mice by inhibiting the LPS-TLR4 pathway.ACE2 通过抑制 LPS-TLR4 通路对 LPS 诱导的小鼠急性肺损伤发挥保护作用。
Exp Mol Pathol. 2020 Apr;113:104350. doi: 10.1016/j.yexmp.2019.104350. Epub 2019 Dec 2.
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Angiotensin-converting enzyme 2 prevents lipopolysaccharide-induced rat acute lung injury via suppressing the ERK1/2 and NF-κB signaling pathways.血管紧张素转化酶 2 通过抑制 ERK1/2 和 NF-κB 信号通路预防脂多糖诱导的大鼠急性肺损伤。
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Ectodomain shedding of angiotensin converting enzyme 2 in human airway epithelia.人呼吸道上皮细胞中血管紧张素转换酶2的胞外域脱落
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Angiotensin-converting enzyme 2 protects from severe acute lung failure.血管紧张素转换酶2可预防严重急性肺衰竭。
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