• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Covid-19 infection and mortality: a physiologist's perspective enlightening clinical features and plausible interventional strategies.

作者信息

Abassi Zaid A, Skorecki Karl, Heyman Samuel Noam, Kinaneh Safa, Armaly Zaher

机构信息

Department of Physiology and Biophysics, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.

Laboratory Medicine, Rambam Medical Center, Haifa, Israel.

出版信息

Am J Physiol Lung Cell Mol Physiol. 2020 May 1;318(5):L1020-L1022. doi: 10.1152/ajplung.00097.2020. Epub 2020 Mar 24.

DOI:10.1152/ajplung.00097.2020
PMID:32207983
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7200872/
Abstract
摘要

相似文献

1
Covid-19 infection and mortality: a physiologist's perspective enlightening clinical features and plausible interventional strategies.新型冠状病毒肺炎感染与死亡率:生理学家视角下的临床特征与可行干预策略解析
Am J Physiol Lung Cell Mol Physiol. 2020 May 1;318(5):L1020-L1022. doi: 10.1152/ajplung.00097.2020. Epub 2020 Mar 24.
2
Coronavirus disease 2019 and the cardiovascular system: Impacts and implications.2019冠状病毒病与心血管系统:影响与启示。
Indian Heart J. 2020 Jan-Feb;72(1):1-6. doi: 10.1016/j.ihj.2020.03.006. Epub 2020 Apr 9.
3
[Renin-Angiotensin-System (RAS) and COVID-19 - On The Prescription of RAS Blockers].[肾素-血管紧张素系统(RAS)与2019冠状病毒病——关于RAS阻滞剂的处方]
Pneumologie. 2020 Sep;74(9):611-614. doi: 10.1055/a-1165-6994. Epub 2020 Sep 11.
4
Angiotensin II suppression in SARS-CoV-2 infection: a therapeutic approach.新型冠状病毒感染中血管紧张素II的抑制作用:一种治疗方法。
Nefrologia (Engl Ed). 2020 May-Jun;40(3):213-216. doi: 10.1016/j.nefro.2020.04.006. Epub 2020 Apr 30.
5
Would ACEIs/ARBs be beneficial for COVID-19 patients without hypertension?血管紧张素转换酶抑制剂/血管紧张素Ⅱ受体阻滞剂对无高血压的新冠患者有益吗?
Pharmacol Res. 2020 Sep;159:104959. doi: 10.1016/j.phrs.2020.104959. Epub 2020 Jun 4.
6
Angiotensin converting enzyme-2 as therapeutic target in COVID-19.血管紧张素转换酶2作为COVID-19的治疗靶点
Diabetes Metab Syndr. 2020 Jul-Aug;14(4):637-639. doi: 10.1016/j.dsx.2020.05.022. Epub 2020 May 12.
7
COVID-19 and fat embolism: a hypothesis to explain the severe clinical outcome in people with obesity.新型冠状病毒肺炎与脂肪栓塞:一种解释肥胖人群严重临床结局的假说。
Int J Obes (Lond). 2020 Aug;44(8):1800-1802. doi: 10.1038/s41366-020-0624-5. Epub 2020 Jun 8.
8
The role of ACEIs/ARBs in COVID-19: Friend or foe?血管紧张素转换酶抑制剂/血管紧张素Ⅱ受体阻滞剂在2019冠状病毒病中的作用:是友还是敌?
Med Hypotheses. 2020 Sep;142:109810. doi: 10.1016/j.mehy.2020.109810. Epub 2020 May 5.
9
Expression of angiotensin-converting enzyme 2 and proteases in COVID-19 patients: A potential role of cellular FURIN in the pathogenesis of SARS-CoV-2.血管紧张素转化酶 2 和蛋白酶在 COVID-19 患者中的表达:细胞 FURIN 在 SARS-CoV-2 发病机制中的潜在作用。
Med Hypotheses. 2020 Oct;143:109893. doi: 10.1016/j.mehy.2020.109893. Epub 2020 May 30.
10
The Effect of Coronavirus Disease 2019 on Cardiovascular Diseases.新型冠状病毒肺炎对心血管疾病的影响。
Arq Bras Cardiol. 2020 Jun 1;114(5):817-822. doi: 10.36660/abc.20200273.

引用本文的文献

1
Regulation of Epithelial Sodium Transport by SARS-CoV-2 Is Closely Related with Fibrinolytic System-Associated Proteins.SARS-CoV-2 通过纤溶系统相关蛋白调节上皮钠离子转运。
Biomolecules. 2023 Mar 23;13(4):578. doi: 10.3390/biom13040578.
2
Computational and Enzymatic Studies of Sartans in SARS-CoV-2 Spike RBD-ACE2 Binding: The Role of Tetrazole and Perspectives as Antihypertensive and COVID-19 Therapeutics.沙坦类药物在 SARS-CoV-2 刺突 RBD-ACE2 结合中的计算和酶学研究:四唑的作用及作为抗高血压和 COVID-19 治疗药物的前景。
Int J Mol Sci. 2023 May 8;24(9):8454. doi: 10.3390/ijms24098454.
3
Respiratory issues in patients with multiple sclerosis as a risk factor during SARS-CoV-2 infection: a potential role for exercise.多发性硬化症患者在感染 SARS-CoV-2 期间的呼吸问题:运动的潜在作用。
Mol Cell Biochem. 2023 Jul;478(7):1533-1559. doi: 10.1007/s11010-022-04610-1. Epub 2022 Nov 21.
4
Expression of SARS-CoV-2-Related Surface Proteins in Non-Small-Cell Lung Cancer Patients and the Influence of Standard of Care Therapy.非小细胞肺癌患者中与严重急性呼吸综合征冠状病毒2相关表面蛋白的表达及标准治疗的影响
Cancers (Basel). 2022 Aug 23;14(17):4074. doi: 10.3390/cancers14174074.
5
Nutraceutical prospects of against the infectious viruses.对抗传染性病毒的营养保健品前景。 (原文“of”后缺少具体内容,此译文根据补充完整后的常见语义翻译)
Food Biosci. 2022 Dec;50:101977. doi: 10.1016/j.fbio.2022.101977. Epub 2022 Aug 30.
6
Actions of Novel Angiotensin Receptor Blocking Drugs, Bisartans, Relevant for COVID-19 Therapy: Biased Agonism at Angiotensin Receptors and the Beneficial Effects of Neprilysin in the Renin Angiotensin System.新型血管紧张素受体阻断药物(比沙坦)在 COVID-19 治疗中的作用:血管紧张素受体的偏激动作用和肾素-血管紧张素系统中内肽酶的有益作用。
Molecules. 2022 Jul 29;27(15):4854. doi: 10.3390/molecules27154854.
7
Diminazene Aceturate Reduces Angiotensin II Constriction and Interacts with the Spike Protein of Severe Acute Respiratory Syndrome Coronavirus 2.乙酰氨基阿维菌素可减轻血管紧张素 II 收缩作用并与严重急性呼吸综合征冠状病毒 2 的刺突蛋白相互作用。
Biomedicines. 2022 Jul 18;10(7):1731. doi: 10.3390/biomedicines10071731.
8
Discovery of a new generation of angiotensin receptor blocking drugs: Receptor mechanisms and in silico binding to enzymes relevant to SARS-CoV-2.新一代血管紧张素受体阻断药物的发现:受体机制及与SARS-CoV-2相关酶的计算机模拟结合
Comput Struct Biotechnol J. 2022;20:2091-2111. doi: 10.1016/j.csbj.2022.04.010. Epub 2022 Apr 9.
9
discovery of non-psychoactive scaffolds in Cannabis halting SARS-CoV-2 host entry and replication machinery.在大麻中发现非精神活性支架可阻止严重急性呼吸综合征冠状病毒2(SARS-CoV-2)进入宿主细胞并破坏其复制机制。
Future Virol. 2022 Mar;0(0). doi: 10.2217/fvl-2021-0309. Epub 2022 Apr 4.
10
A Novel Soluble ACE2 Protein Provides Lung and Kidney Protection in Mice Susceptible to Lethal SARS-CoV-2 Infection.一种新型可溶性 ACE2 蛋白可保护易感染致死性 SARS-CoV-2 感染的小鼠肺部和肾脏。
J Am Soc Nephrol. 2022 Jul;33(7):1293-1307. doi: 10.1681/ASN.2021091209. Epub 2022 Mar 2.

本文引用的文献

1
Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein.严重急性呼吸系统综合征冠状病毒 2 刺突糖蛋白的结构、功能和抗原性。
Cell. 2020 Apr 16;181(2):281-292.e6. doi: 10.1016/j.cell.2020.02.058. Epub 2020 Mar 9.
2
Clinical Characteristics of Coronavirus Disease 2019 in China.《中国 2019 年冠状病毒病临床特征》
N Engl J Med. 2020 Apr 30;382(18):1708-1720. doi: 10.1056/NEJMoa2002032. Epub 2020 Feb 28.
3
Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study.中国武汉严重 COVID-19 患者的临床病程和结局:一项单中心、回顾性、观察性研究。
Lancet Respir Med. 2020 May;8(5):475-481. doi: 10.1016/S2213-2600(20)30079-5. Epub 2020 Feb 24.
4
Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan, China.中国武汉 140 名 SARS-CoV-2 感染患者的临床特征。
Allergy. 2020 Jul;75(7):1730-1741. doi: 10.1111/all.14238. Epub 2020 Feb 27.
5
The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade.新型冠状病毒 2019-nCoV 的刺突糖蛋白含有弗林蛋白酶样裂解位点,而同一进化枝的 CoV 中则没有。
Antiviral Res. 2020 Apr;176:104742. doi: 10.1016/j.antiviral.2020.104742. Epub 2020 Feb 10.
6
Receptor Recognition by the Novel Coronavirus from Wuhan: an Analysis Based on Decade-Long Structural Studies of SARS Coronavirus.新型冠状病毒受体识别:基于 SARS 冠状病毒长达十年结构研究的分析。
J Virol. 2020 Mar 17;94(7). doi: 10.1128/JVI.00127-20.
7
Design, Synthesis, and Characterization of Macrocyclic Inhibitors of the Proprotein Convertase Furin.大环抑制剂脯氨酰内肽酶 furin 的设计、合成与表征。
ChemMedChem. 2019 Mar 22;14(6):673-685. doi: 10.1002/cmdc.201800807. Epub 2019 Feb 20.
8
Post-transcriptional modification of pro-BNP in heart failure: is glycosylation and circulating furin key for cardiovascular homeostasis?心力衰竭中脑钠肽前体的转录后修饰:糖基化和循环中的弗林蛋白酶对心血管稳态至关重要吗?
Eur Heart J. 2014 Nov 14;35(43):3001-3. doi: 10.1093/eurheartj/ehu381. Epub 2014 Sep 21.
9
BNP molecular forms and processing by the cardiac serine protease corin.脑钠肽分子形式及其在心氨酸蛋白酶 corin 作用下的加工。
Adv Clin Chem. 2013;61:1-31. doi: 10.1016/b978-0-12-407680-8.00001-4.
10
Devil and angel in the renin-angiotensin system: ACE-angiotensin II-AT1 receptor axis vs. ACE2-angiotensin-(1-7)-Mas receptor axis.肾素-血管紧张素系统中的魔鬼与天使:ACE-血管紧张素II-AT1受体轴与ACE2-血管紧张素-(1-7)-Mas受体轴
Hypertens Res. 2009 Jul;32(7):533-6. doi: 10.1038/hr.2009.74. Epub 2009 May 22.