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机器学习方法在肾脏疾病中的应用:希望还是炒作?

Applications of machine learning methods in kidney disease: hope or hype?

机构信息

Division of Nephrology, Department of Medicine The Charles Bronfman Institute of Personalized Medicine The Hasso Plattner Institute for Digital Health The BioMe Phenomics Center, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

出版信息

Curr Opin Nephrol Hypertens. 2020 May;29(3):319-326. doi: 10.1097/MNH.0000000000000604.

Abstract

PURPOSE OF REVIEW

The universal adoption of electronic health records, improvement in technology, and the availability of continuous monitoring has generated large quantities of healthcare data. Machine learning is increasingly adopted by nephrology researchers to analyze this data in order to improve the care of their patients.

RECENT FINDINGS

In this review, we provide a broad overview of the different types of machine learning algorithms currently available and how researchers have applied these methods in nephrology research. Current applications have included prediction of acute kidney injury and chronic kidney disease along with progression of kidney disease. Researchers have demonstrated the ability of machine learning to read kidney biopsy samples, identify patient outcomes from unstructured data, and identify subtypes in complex diseases. We end with a discussion on the ethics and potential pitfalls of machine learning.

SUMMARY

Machine learning provides researchers with the ability to analyze data that were previously inaccessible. While still burgeoning, several studies show promising results, which will enable researchers to perform larger scale studies and clinicians the ability to provide more personalized care. However, we must ensure that implementation aids providers and does not lead to harm to patients.

摘要

目的综述:电子健康记录的普及、技术的改进以及连续监测的可用性产生了大量的医疗保健数据。肾病学研究人员越来越多地采用机器学习来分析这些数据,以改善患者的护理。

最新发现:在这篇综述中,我们提供了当前可用的不同类型的机器学习算法的广泛概述,以及研究人员如何将这些方法应用于肾病学研究。目前的应用包括急性肾损伤和慢性肾脏病的预测以及肾脏病的进展。研究人员已经证明了机器学习从非结构化数据中读取肾脏活检样本、识别患者结局以及识别复杂疾病亚型的能力。最后我们讨论了机器学习的伦理和潜在陷阱。

总结:机器学习为研究人员提供了分析以前无法访问的数据的能力。虽然还处于萌芽阶段,但有几项研究显示出了有希望的结果,这将使研究人员能够进行更大规模的研究,使临床医生能够提供更个性化的护理。然而,我们必须确保实施有助于提供者,而不会对患者造成伤害。

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