Department of Obstetrics and Gynecology, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Department of Obstetrics and Gynecology, "I. Cantacuzino" Clinical Hospital, 030167 Bucharest, Romania.
Medicina (Kaunas). 2020 Mar 29;56(4):152. doi: 10.3390/medicina56040152.
Synchronous gynecological malignancies are rarely encountered, and most often these cases are represented by synchronous ovarian and endometrial cancer. The aim of this paper is to present the case of a 53-year-old patient who was diagnosed with synchronous cervical and ovarian cancer. The patient had been initially investigated for vaginal bleeding and was submitted to a biopsy confirming the presence of a cervical adenocarcinoma. Once the diagnostic of malignancy was confirmed, the patient was submitted to a computed tomography which revealed the presence of large abdominal tumoral nodules of peritoneal carcinomatosis and was submitted to palliative chemotherapy with poor response. Eighteen months later she developed intestinal obstruction and was submitted to surgery. At that moment, synchronous ovarian and cervical tumors were diagnosed. Total radical hysterectomy with bilateral adnexectomy, pelvic and para-aortic lymph node dissection, omentectomy, and pelvic peritonectomy was performed; in the meantime, the histopathological studies confirmed the presence of two synchronous malignancies. : Although synchronous lesions are rarely encountered, this eventuality should not be omitted. In such cases, surgery should be taken in consideration and the intent of radicality should regard both lesions.
同时性妇科恶性肿瘤很少见,大多数情况下这些病例表现为同时性卵巢和子宫内膜癌。本文旨在介绍一例 53 岁同时性宫颈和卵巢癌患者的病例。该患者最初因阴道出血接受检查,并进行了活检,证实存在宫颈腺癌。一旦恶性肿瘤的诊断得到确认,患者接受了计算机断层扫描,发现存在大量腹部肿瘤性腹膜癌结节,并接受姑息性化疗,但反应不佳。18 个月后,她出现肠梗阻并接受了手术。此时,诊断出同时性卵巢和宫颈肿瘤。进行了根治性子宫切除术、双侧附件切除术、盆腔和主动脉旁淋巴结清扫术、网膜切除术和盆腔腹膜切除术;同时,组织病理学研究证实存在两种同时性恶性肿瘤。
虽然同时性病变很少见,但不应忽视这种可能性。在这种情况下,应考虑手术,根治性意图应同时针对两个病变。