Centro de Salud Callosa del Segura, Paseo Enrique Tierno Galvan, 19, E-03360 Alicante, Spain.
CEBAS-CSIC, Department of Plant Nutrition. Aquaporins Group, Campus Universitario de Espinardo-25, E-30100 Murcia, Spain.
Molecules. 2020 Mar 30;25(7):1591. doi: 10.3390/molecules25071591.
vegetables and their components, the glucosinolates, have been suggested as good candidates as dietary coadjutants to improve health in non-communicable diseases (NCDs). Different preclinical and clinical studies have been performed in the last decade; however, some concerns have been posed on the lack of established and standardized protocols. The different concentration of bioactive compounds used, time of intervention or sample size, and the lack of blinding are some factors that may influence the studies' outcomes. This review aims to analyze the critical points of the studies performed with -related biomolecules and propose some bases for future trials in order to avoid biases.
蔬菜及其成分，如硫代葡萄糖苷，被认为是改善非传染性疾病（NCDs）健康的良好膳食辅助物。在过去十年中，已经进行了不同的临床前和临床研究；然而，人们对缺乏既定和标准化方案提出了一些担忧。生物活性化合物的不同浓度、干预时间或样本量，以及缺乏盲法，是可能影响研究结果的一些因素。本综述旨在分析与相关生物分子相关研究的关键点，并为未来的试验提出一些基础，以避免偏倚。
