Zhong Ling-Yun, Cui Mei-Na, Yang Ming, Gong Qian-Feng
National Heritage Base of Processing of Chinese Herb Medicine,Key Laboratory of Modern Research of Traditional Processing of Chinese Herb Medicine of Jiangxi Province,Jiangxi University of Traditional Chinese Medicine Nanchang 330004,China.
Zhongguo Zhong Yao Za Zhi. 2019 Dec;44(23):5109-5113. doi: 10.19540/j.cnki.cjcmm.20190916.301.
The processing of Chinese herb medicine( PCHM) is the premise and necessity of treating diseases in traditional Chinese medicine( TCM). After processing,Chinese herbal medicine can achieve the effects of correcting odor,inducing channel tropism,changing drug properties and reducing toxicity. As the most important part of TCM theory system,Chinese medicine property,involving four odors and five flavors,ascending and descending,channel tropism,toxicity and side effects. In recent years,with the development of modern science and technology,many researches on the changes of properties of Chinese herb medicines by PCHM have been reported. In this paper,the researches in four aspects of processing method,chemical composition,medicinal effect and biological effect on properties changes by PCHM were reviewed,so as to discuss the modern research ideas and technologies,and explain the importance of the increase of clinical efficacy of TCM through property changes by PCHM. In the end,the future research ideas and cutting-edge technologies were discussed to make the studies on property changes by PCHM more systematic and deeper.
中药炮制是中医治病的前提和必由之路。中药经过炮制后，可达到矫味、引经、改变药性、降低毒性等效果。中药药性作为中医理论体系的重要组成部分，涉及四气五味、升降浮沉、归经、毒性及副作用等。近年来，随着现代科学技术的发展，已有许多关于中药炮制对中药药性影响的研究报道。本文综述了中药炮制在炮制方法、化学成分、药理作用、生物学效应四个方面对中药药性影响的研究，旨在探讨现代研究思路与技术，阐明中药炮制通过药性改变提高临床疗效的重要性。最后，对未来的研究思路和前沿技术进行了探讨，以使中药炮制对药性影响的研究更加系统和深入。
