Fernandez-Nieto D, Jimenez-Cauhe J, Ortega-Quijano D, Burgos-Blasco Patricia, Pindado-Ortega Cristina, Bea-Ardebol S
Department of Dermatology, Hospital Universitario Ramón y Cajal, Madrid.
Dermatol Online J. 2020 Feb 15;26(2):13030/qt3k90n5s9.
Disseminated herpes simplex virus (HSV) is mainly seen in immunocompromised individuals. Atypical lesions can be present in both primary infection and reactivation disease. Compared with the general population, inmunocompromised hosts are at greater risk of increased persistency and severity of clinical manifestations, including severe systemic involvement such as esophagitis, meningitis, and hepatitis. Herein, we report the case of a liver transplant recipient with atypical disseminated herpes simplex virus-1 complicated by HSV-related hepatitis. Dermatological consultation and histological assessment were crucial for a correct diagnosis and treatment.
播散性单纯疱疹病毒（HSV）主要见于免疫功能低下的个体。原发性感染和复发疾病中均可出现非典型病变。与普通人群相比，免疫功能低下的宿主出现临床表现持续时间延长和病情加重的风险更高，包括食管炎、脑膜炎和肝炎等严重的全身受累情况。在此，我们报告一例肝移植受者发生非典型播散性单纯疱疹病毒1型感染并伴有HSV相关肝炎的病例。皮肤科会诊和组织学评估对正确诊断和治疗至关重要。
