Department of Nephrology, Zhongnan Hospital, Wuhan University, Wuhan, China.
Laboratory Medicine, Zhongnan Hospital, Wuhan University, Wuhan, China.
Am J Kidney Dis. 2020 Jul;76(1):141-143. doi: 10.1053/j.ajkd.2020.03.009. Epub 2020 Mar 31.
In December 2019, an outbreak of coronavirus disease 2019 (COVID-19) due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) began in China and spread rapidly worldwide. It is unknown whether hemodialysis patients represent a distinct group of patients with certain characteristics that may make them susceptible to infection or severe disease. In this case report, we describe the clinical and epidemiologic features of COVID-19 infection in 201 maintenance hemodialysis patients in Zhongnan Hospital of Wuhan University, including 5 maintenance hemodialysis patients who contracted COVID-19 infection. Of the 5 patients with COVID-19 infection, one had a definite history of contact with an infected person. The age range of the patients was 47 to 67 years. Diarrhea (80%), fever (60%), and fatigue (60%) were the most common symptoms. Lymphopenia occurred in all patients. Computed tomography of the chest showed ground glass opacity in the lungs of all patients. Up to February 13, 2020, none of the patients had developed severe complications (acute respiratory distress syndrome, shock, or multiple organ dysfunction) or died.
2019 年 12 月，一种由严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）引起的 2019 年冠状病毒病（COVID-19）在中国爆发，并迅速在全球范围内传播。目前尚不清楚血液透析患者是否代表一组具有某些特征的特定患者，这些特征可能使他们容易感染或患上严重疾病。在本病例报告中，我们描述了武汉大学中南医院 201 例维持性血液透析患者 COVID-19 感染的临床和流行病学特征，包括 5 例确诊为 COVID-19 感染的维持性血液透析患者。在 5 例 COVID-19 感染患者中，有 1 例有明确的与感染者接触史。患者年龄为 47 至 67 岁。腹泻（80%）、发热（60%）和乏力（60%）是最常见的症状。所有患者均出现淋巴细胞减少症。胸部计算机断层扫描显示所有患者肺部均有磨玻璃样混浊。截至 2020 年 2 月 13 日，尚无患者发生严重并发症（急性呼吸窘迫综合征、休克或多器官功能障碍）或死亡。
