Professor, Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC, United States; Associate Director, Population Sciences and Cancer Disparities, Hollings Cancer Center, Medical University of South Carolina, Charleston, SC United States; SmartState Endowed Chair in Cancer Disparities Research, South Carolina State University, Orangeburg, SC, United States.
Academic Affairs Faculty, Medical University of South Carolina, Charleston, SC, United States.
Adv Cancer Res. 2020;146:115-137. doi: 10.1016/bs.acr.2020.01.007. Epub 2020 Mar 12.
Human papillomavirus (HPV) infection is the primary risk factor for cervical cancer. While the HPV vaccine significantly reduces the risk of HPV infection and subsequent cervical cancer diagnosis, underuse is linked to lack of knowledge of its effectiveness in preventing cervical cancer. The purpose of this study was to evaluate a cancer educational intervention (titled "MOVENUP") to improve knowledge of cervical cancer, HPV, and the HPV vaccine among predominantly African American communities in South Carolina. The MOVENUP cancer educational intervention was conducted among participants residing in nine South Carolina counties who were recruited by community partners. The 4.5-h MOVENUP cancer educational intervention included a 30-min module on cervical cancer, HPV, and HPV vaccination. A six-item investigator-developed instrument was used to evaluate pre- and post-intervention changes in knowledge related to these content areas. Ninety-three percent of the 276 participants were African American. Most participants reporting age and gender were 50+ years (73%) and female (91%). Nearly half of participants (46%) reported an annual household income <$40,000 and 49% had not graduated from college. Statistically significant changes were observed at post-test for four of six items on the knowledge scale (P<0.05), as compared to pre-test scores. For the two items on the scale in which statistically significant changes were not observed, this was due primarily due to a baseline ceiling effect.
人乳头瘤病毒（HPV）感染是宫颈癌的主要危险因素。HPV 疫苗显著降低了 HPV 感染和随后宫颈癌诊断的风险，但由于对其预防宫颈癌有效性的认识不足，导致疫苗接种率较低。本研究旨在评估一项癌症教育干预措施（名为“MOVENUP”），以提高南卡罗来纳州主要为非裔美国人社区对宫颈癌、HPV 和 HPV 疫苗的认识。MOVENUP 癌症教育干预措施在南卡罗来纳州 9 个县的参与者中进行，由社区合作伙伴招募。为期 4.5 小时的 MOVENUP 癌症教育干预措施包括一个关于宫颈癌、HPV 和 HPV 疫苗接种的 30 分钟模块。使用由研究人员开发的六项目调查工具评估与这些内容领域相关的知识在干预前后的变化。276 名参与者中有 93%是非裔美国人。大多数报告年龄和性别的参与者为 50 岁以上（73%）和女性（91%）。近一半的参与者（46%）报告年收入<40,000 美元，49%没有大学毕业。与预测试分数相比，在测试后，知识量表的六个项目中的四个项目的分数有统计学意义上的显著变化（P<0.05）。在量表上的两个没有观察到统计学显著变化的项目中，这主要是由于基线上限效应。
