磷脂 - 水分散体系六方HII相中的酰基链取向有序性。
Acyl chain orientational order in the hexagonal HII phase of phospholipid-water dispersions.
作者信息
Sternin E, Fine B, Bloom M, Tilcock C P, Wong K F, Cullis P R
机构信息
Department of Physics, University of British Columbia.
出版信息
Biophys J. 1988 Oct;54(4):689-94. doi: 10.1016/S0006-3495(88)83004-2.
Abstract
The deuterium nuclear magnetic resonance (2H NMR) spectrum of perdeuterated tetradecanol in a mixture of 1-palmitoyl-2-oleoyl-phosphatidylethanolamine (POPE) and water was used to compare the variation of the acyl chain orientational order parameter, S(n), with carbon position, n, in the liquid crystalline lamellar (L alpha) and hexagonal (HII) phases. The characteristics independence of S(n) with n (plateau) normally observed in the L alpha phase is replaced by a more rapid decrease of S(n) with n in the HII phase. It is suggested that as a consequence of the geometrical characteristics of the HII phase, there is an increase in conformational freedom available to different parts of the acyl chain.
摘要
在1-棕榈酰-2-油酰基磷脂酰乙醇胺（POPE）和水的混合物中，全氘代十四烷醇的氘核磁共振（2H NMR）光谱用于比较液晶层状（Lα）相和六方（HII）相中酰基链取向序参数S(n)随碳位置n的变化。通常在Lα相中观察到的S(n)与n的特征独立性（平台期）在HII相中被S(n)随n更快的下降所取代。有人认为，由于HII相的几何特征，酰基链不同部分的构象自由度增加。
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