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从费尔南德·维达尔鼻炎综合征和慢性鼻窦炎到全黏液纤毛疾病。

From Fernand Widal rhinitis syndrome and chronic sinusitis to total muco-ciliary disease.

作者信息

Mathé G, Abitol J

机构信息

Département des Maladies Sanguines, Hôpital Paul-Brousse, Villejuif, France.

出版信息

Biomed Pharmacother. 1988;42(8):489-92.

PMID:3224158
Abstract

It is claimed that 25% of the total population show symptoms of a muco-ciliary chronic sinusitis, presenting as a posterior catharrh that can be confirmed by computerized tomography and by prolonged sinuso-nasal saccharine clearance. This manifestation of the mucus ciliary transport syndrome may be associated with other disorders (rhinitis, otitis, bronchitis, irritable colon, sterility and dextrocardia). The role of aspirin and intolerance to other drugs or chemicals especially anti-inflammatory drugs, has been implicated. Acid air pollution may play a part, as the respiratory mucus does not tolerate an acid pH. Alkaline aerosols and theophyllin which activates cilia mobility, usually increase mucus fluidity and facilitate its clearance from the sinuses.

摘要

据称,总人口的25%表现出黏液纤毛慢性鼻窦炎的症状,表现为后鼻黏膜炎,这可通过计算机断层扫描和延长的鼻窦糖精清除试验来确诊。黏液纤毛运输综合征的这种表现可能与其他疾病(鼻炎、中耳炎、支气管炎、肠易激综合征、不育症和右位心)有关。阿司匹林以及对其他药物或化学物质尤其是抗炎药的不耐受性也被认为与之有关。酸性空气污染可能起一定作用,因为呼吸道黏液不耐受酸性pH值。碱性气雾剂和可激活纤毛运动的茶碱通常会增加黏液流动性,并促进其从鼻窦清除。

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