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肺动脉高压的临床进展

Clinical update on pulmonary hypertension.

作者信息

Yaghi Salim, Novikov Anastasia, Trandafirescu Theo

机构信息

Queens Hospital Center, Medicine, Mount Sinai Medical Center, Queens, New York, USA.

Queens Hospital Center, Medicine, Mount Sinai Medical Center, Queens, New York, USA

出版信息

J Investig Med. 2020 Apr;68(4):821-827. doi: 10.1136/jim-2020-001291. Epub 2020 Apr 1.

Abstract

Pulmonary hypertension (PH) is a chronic, complex and challenging disease. Advances in treatment are for the subset of patients with pulmonary arterial hypertension. Selected review of the literature was conducted incorporating the European Society of Cardiology/European Respiratory Society 2015 guidelines and recommendations from the Sixth World Symposium on Pulmonary Hypertension. PH is classified into five groups based on WHO classification. Echocardiography remains the initial test of choice, and careful assessment of the right system aids in the diagnosis and prognosis of the disease. Right heart catheterization remains the gold standard of diagnosis and key guidance of treatment. Multidisciplinary approach is recommended for the care of patients with PH. Treatment selection is based on individual risk stratification of patients, and early referral to specialized PH centers improves outcomes of patients. Treating PH is complex and is best carried out in PH centers and with multidisciplinary approach. Early diagnosis and referral to those centers are key not to delay treatment.

摘要

肺动脉高压(PH)是一种慢性、复杂且具有挑战性的疾病。治疗进展适用于肺动脉高压患者亚组。结合欧洲心脏病学会/欧洲呼吸学会2015年指南以及第六届世界肺动脉高压研讨会的建议,对文献进行了精选回顾。根据世界卫生组织(WHO)分类,PH分为五组。超声心动图仍是首选的初始检查,对右心系统的仔细评估有助于疾病的诊断和预后判断。右心导管检查仍是诊断的金标准和治疗的关键指导。建议采用多学科方法来护理PH患者。治疗选择基于患者的个体风险分层,早期转诊至专门的PH中心可改善患者预后。治疗PH很复杂,最好在PH中心并采用多学科方法进行。早期诊断并转诊至这些中心是不延误治疗的关键。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56f0/7231433/25e1787ad5ee/jim-2020-001291f01.jpg

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