Department of Chemistry, Visva-Bharati (A Central University) Santiniketan, 731235, West Bengal, India.
Org Biomol Chem. 2020 Apr 29;18(16):3093-3097. doi: 10.1039/d0ob00353k.
Switchable Rh(iii)-catalyzed highly regioselective hydroarylation and oxidative arylation of maleimides with 2-arylindazoles via C-H activation have been demonstrated. The reaction affords 3-(2-(2H-indazol-2-yl)phenyl)succinimide and 3-(2-(2H-indazol-2-yl)phenyl)maleimide derivatives in high yields with wide functional group tolerance. A mechanistic study was performed to depict C-H bond cleavage that might be involved in the turnover limiting step.
通过 C-H 活化，展示了铑(III)催化的马来酰亚胺与 2-芳基吲哚的可切换高区域选择性氢芳基化和氧化芳基化反应。该反应以高产率和广泛的官能团容忍度得到了 3-(2-(2H-吲哚-2-基)苯基)琥珀酰亚胺和 3-(2-(2H-吲哚-2-基)苯基)马来酰亚胺衍生物。进行了一项机理研究，以描绘可能涉及周转限制步骤的 C-H 键断裂。
