Department of Mechanical Engineering, University of Birmingham, Birmingham, UK.
Cardiac Department, Aberdeen Royal Infirmary, Aberdeen, UK.
J Anat. 2020 Aug;237(2):209-224. doi: 10.1111/joa.13196. Epub 2020 Apr 3.
The mitral valve is a complex anatomical structure whose physiological functioning relies on the biomechanical properties and structural integrity of its components. Their compromise can lead to mitral valve dysfunction, associated with morbidity and mortality. Therefore, a review on the morphometry of the mitral valve is crucial, more specifically on the importance of valve dimensions and shape for its function. This review initially provides a brief background on the anatomy and physiology of the mitral valve, followed by an analysis of the morphological information available. A characterisation of mathematical descriptions of several parts of the valve is performed and the impact of different dimensions and shape changes in disease is then outlined. Finally, a section regarding future directions and recommendations for the use of morphometric information in clinical analysis of the mitral valve is presented.
二尖瓣是一个复杂的解剖结构,其生理功能依赖于其各个组成部分的生物力学特性和结构完整性。这些组成部分的功能障碍会导致二尖瓣功能障碍,并伴有发病率和死亡率。因此,对二尖瓣的形态计量学进行综述至关重要,特别是对瓣膜尺寸和形状对其功能的重要性进行综述。本综述首先简要介绍了二尖瓣的解剖结构和生理学,然后对现有的形态学信息进行了分析。对瓣膜几个部分的数学描述进行了特征描述,并概述了不同尺寸和形状变化在疾病中的影响。最后,介绍了未来在二尖瓣的临床分析中使用形态计量学信息的方向和建议。