From the Institute of Molecular Virology (IMV), University Hospital Münster, Münster, Germany.
Department of Anaesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Munster, Germany.
Anesth Analg. 2020 Jul;131(1):93-96. doi: 10.1213/ANE.0000000000004845.
In late December 2019, several cases of pneumonia of unknown origin were reported from China, which in early January 2020 were announced to be caused by a novel coronavirus. The virus was later denominated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and defined as the causal agent of coronavirus disease 2019 (COVID-19). Despite massive attempts to contain the disease in China, the virus has spread globally, and COVID-19 was declared a pandemic by the World Health Organization (WHO) in March 2020. Here we provide a short background on coronaviruses, and describe in more detail the novel SARS-CoV-2 and attempts to identify effective therapies against COVID-19.
2019 年 12 月下旬,中国报告了几例不明原因的肺炎病例,这些病例在 2020 年 1 月初被宣布是由一种新型冠状病毒引起的。该病毒后来被命名为严重急性呼吸综合征冠状病毒 2(SARS-CoV-2),并被定义为 2019 年冠状病毒病(COVID-19)的病原体。尽管中国采取了大规模措施来控制这种疾病,但该病毒已在全球范围内传播,世界卫生组织(WHO)于 2020 年 3 月宣布 COVID-19 为大流行。在这里,我们提供了有关冠状病毒的简要背景,并更详细地描述了新型 SARS-CoV-2 以及试图确定针对 COVID-19 的有效疗法的情况。