Dalin Dagmar Abelone, Vermehren Charlotte, Jensen Anette Kobberø, Unkerskov Janne, Andersen Jon Trærup
Department of Clinical Pharmacology, Copenhagen University Hospital Bispebjerg, Copenhagen DK-2400, Denmark.
Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark.
Pharmacy (Basel). 2020 Mar 31;8(2):57. doi: 10.3390/pharmacy8020057.
Polypharmacy increases the risk of hospitalization but may be reduced by medication review. The study objective is to describe and evaluate a method for conducting medication review in general practice by an interdisciplinary medication team of pharmacists and physicians-in this case conducted by a team from the Department of Clinical Pharmacology-based on information concerning medication, diagnosis, relevant laboratory data and medical history supplied by the general practitioner. We discussed the medication review with the patients' general practitioners and received feedback from them regarding acceptance rates of the recommended changes. Ninety-four patients with a total of 1471 prescriptions were included. A medication change was recommended for nearly half of the prescriptions (48%); at least one change of medication was recommended for all patients. The acceptance rate for recommended medication changes was 55%, corresponding to a mean of 4.2 accepted recommendations per patient. For 18% of all 1471 prescriptions, the general practitioner agreed either to discontinue (stop the medication completely) or reduce the dose of the medication. This method is thorough, but since it requires several healthcare professionals, it is rather time-consuming. There is a need to support medication review in general practice, but although this method may be too time consuming in most cases, it may nevertheless prove to be a useful tool managing the most complicated patients.
多重用药会增加住院风险，但通过药物审查可能会降低该风险。本研究的目的是描述和评估一种由药剂师和医生组成的跨学科药物团队在全科医疗中进行药物审查的方法——在本案例中，由临床药理学系的一个团队基于全科医生提供的有关用药、诊断、相关实验室数据和病史的信息来开展。我们与患者的全科医生讨论了药物审查情况，并收到了他们对推荐更改的接受率的反馈。纳入了94名患者，共有1471张处方。近一半的处方（48%）被建议进行药物更改；所有患者均至少有一项药物更改建议。推荐药物更改的接受率为55%，相当于每位患者平均有4.2项更改建议被接受。在所有1471张处方中，18%的处方，全科医生同意停用（完全停止用药）或减少药物剂量。这种方法很全面，但由于需要多名医疗保健专业人员参与，相当耗时。全科医疗中需要支持药物审查，虽然这种方法在大多数情况下可能过于耗时，但它可能仍是管理最复杂患者的有用工具。
