Department of Physiology and "José MataixVerdú" Institute of Nutrition and Food Technology (INYTA), University of Granada, 18071 Granada, Spain.
Pediatric Gastroenterology and Nutrition Unit, Hospital Regional Universitario de Malaga, 29010 Málaga, Spain.
Nutrients. 2020 Mar 21;12(3):844. doi: 10.3390/nu12030844.
The current study assesses whether the use of a gluten-free diet (GFD) is sufficient for maintaining correct iron status in children with celiac disease (CD). The study included 101 children. The celiac group ( = 68) included children with CD, with long (> 6 months) ( = 47) or recent (< 6 months) ( = 21) adherence to a GFD. The control group ( = 43) included healthy children. Dietary assessment was performed by a food frequency questionnaire and a 3-day food record. Celiac children had lower iron intake than controls, especially at the beginning of GFD ( < 0.01). The group CD-GFD >6 months showed a higher intake of cobalamin, meat derivatives and fish compared to that of CD-GFD <6 months (all, < 0.05). The control group showed a higher consumption of folate, iron, magnesium, selenium and meat derivatives than that of children CD-GFD >6 months (all, < 0.05). Control children also showed a higher consumption of folate and iron compared to that of children CD-GFD <6 months (both, < 0.05). The diet of celiac children was nutritionally less balanced than that of the control. Participation of dietitians is necessary in the management of CD to guide the GFD as well as assess the inclusion of iron supplementation and other micronutrients that may be deficient.
本研究评估了在患有乳糜泻 (CD) 的儿童中，无麸质饮食 (GFD) 是否足以维持正确的铁状态。研究纳入了 101 名儿童。乳糜泻组（=68）包括患有 CD 的儿童，分为长期 (>6 个月)（=47）或近期 (<6 个月)（=21）遵循 GFD。对照组（=43）包括健康儿童。通过食物频率问卷和 3 天食物记录进行膳食评估。乳糜泻儿童的铁摄入量低于对照组，尤其是在开始 GFD 时（<0.01）。CD-GFD >6 个月组的钴胺素、肉类衍生物和鱼类的摄入量高于 CD-GFD <6 个月组（均<0.05）。对照组的叶酸、铁、镁、硒和肉类衍生物的摄入量高于 CD-GFD >6 个月组（均<0.05）。对照组的叶酸和铁的摄入量也高于 CD-GFD <6 个月组（均<0.05）。乳糜泻儿童的饮食在营养上不如对照组均衡。营养师的参与对于 CD 的管理是必要的，以指导 GFD，并评估是否需要补充铁和其他可能缺乏的微量营养素。
