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脑发育的个体差异建模。

Modeling Individual Differences in Brain Development.

机构信息

Brain and Development Research Center, Developmental and Educational Psychology Unit, Leiden University, Leiden; Adolescent Development Research Center, Utrecht University, Utrecht, the Netherlands; Department of Psychology, Education and Child Studies, Erasmus University, Rotterdam, the Netherlands.

Department of Psychology, University of Oregon, Eugene, Oregon.

出版信息

Biol Psychiatry. 2020 Jul 1;88(1):63-69. doi: 10.1016/j.biopsych.2020.01.027. Epub 2020 Feb 11.

Abstract

Within the field of developmental cognitive neuroscience, there is an increasing interest in studying individual differences in human brain development in order to predict mental health outcomes. So far, however, most longitudinal neuroimaging studies focus on group-level estimates. In this review, we highlight longitudinal neuroimaging studies that have moved beyond group-level estimates to illustrate the heterogeneity in patterns of brain development. We provide practical methodological recommendations on how longitudinal neuroimaging datasets can be used to understand heterogeneity in human brain development. Finally, we address how taking an individual-differences approach in developmental neuroimaging studies could advance our understanding of why some individuals develop mental health disorders.

摘要

在发展认知神经科学领域,人们越来越感兴趣于研究人类大脑发育的个体差异,以预测心理健康结果。然而,到目前为止,大多数纵向神经影像学研究都集中在群体水平的估计上。在这篇综述中,我们强调了超越群体水平估计的纵向神经影像学研究,以说明大脑发育模式的异质性。我们提供了关于如何使用纵向神经影像学数据集来理解人类大脑发育异质性的实用方法建议。最后,我们探讨了在发展神经影像学研究中采用个体差异方法如何增进我们对为什么一些人会发展出心理健康障碍的理解。

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