无线电信号感知和信号处理监测痴呆症的行为症状：案例研究。
Radio Signal Sensing and Signal Processing to Monitor Behavioral Symptoms in Dementia: A Case Study.
机构信息
Division of Geriatric Psychiatry, McLean Hospital (IVV, BPF, PM, RM, KH), Belmont, MA; Harvard Medical School (IVV, BPF), Boston, MA.
Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology (ZK, C-YH, UM, KH), Cambridge, MA.
出版信息
Am J Geriatr Psychiatry. 2020 Aug;28(8):820-825. doi: 10.1016/j.jagp.2020.02.012. Epub 2020 Mar 8.
OBJECTIVES
Alzheimer's Disease (AD)-related behavioral symptoms (i.e. agitation and/or pacing) develop in nearly 90% of AD patients. In this N = 1 study, we provide proof-of-concept of detecting changes in movement patterns that may reflect underlying behavioral symptoms using a highly novel radio sensor and identifying environmental triggers.
METHODS
The Emerald device is a Wi-Fi-like box without on-body sensors, which emits and processes radio-waves to infer patient movement, spatial location and activity. It was installed for 70 days in the room of patient 'E', exhibiting agitated behaviors.
RESULTS
Daily motion episode aggregation revealed motor activity fluctuation throughout the data collection period which was associated with potential socio-environmental triggers. We did not detect any adverse events attributable to the use of the device.
CONCLUSION
This N-of-1 study suggests the Emerald device is feasible to use and can potentially yield actionable data regarding behavioral symptom management. No active or potential device risks were encountered.
目的
近 90%的阿尔茨海默病（AD）患者会出现与 AD 相关的行为症状（即躁动和/或踱步）。在这项 N=1 的研究中，我们使用一种高度新颖的无线电传感器来检测可能反映潜在行为症状的运动模式变化，并识别环境触发因素，以此提供概念验证。
方法
Emerald 设备是一个没有体侧传感器的类似 Wi-Fi 的盒子，它通过发射和处理无线电波来推断患者的运动、空间位置和活动。该设备在表现出躁动行为的患者“E”的房间内安装了 70 天。
结果
日常运动事件聚合显示，整个数据收集期间的运动活动存在波动，与潜在的社会环境触发因素有关。我们未检测到任何与设备使用相关的不良事件。
结论
这项单病例研究表明，Emerald 设备是可行的，可以针对行为症状管理产生可采取行动的数据。未发现任何与设备相关的实际或潜在风险。
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