Key Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement/Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou, 510650, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
Key Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement/Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou, 510650, China; Sericultural & Agri-Food Research Institute, Guangdong Academy of Agricultural Sciences/Key Laboratory of Functional Foods, Ministry of Agriculture and Rural Affairs/Guangdong Key Laboratory of Agricultural Products Processing, Guangzhou, 510610, China.
Phytochemistry. 2020 Jun;174:112364. doi: 10.1016/j.phytochem.2020.112364. Epub 2020 Apr 1.
Ten undescribed dihydrochalcone C-glycosides, carambolasides R1‒R3, S1, S2, T1‒T3, 3-hydroxycarambolaside T1, and 3-hydroxycarambolaside P were isolated along with carambolasides I and P from the leaves of Averrhoa carambola L. (Oxalidaceae). Their structures were determined by spectroscopic and chemical methods. Among them, carambolasides P, T1, T2, and I with contents of 22.78, 14.39, 4.93, and 1.87 mg g dry wt., respectively, were shown to be abundant in the leaves by HPLC analysis. All the compounds showed more potent ABTS radical cation scavenging activity than l-ascorbic acid. 3-Hydroxycarambolaside T1 and 3-hydroxycarambolaside P also demonstrated moderate DPPH radical scavenging activity. Further, carambolaside R3, 3-hydroxycarambolaside T1, and 3-hydroxycarambolaside P exhibited weak in vitro porcine pancreatic lipase inhibitory activity.
从桃金娘科植物杨桃（Averrhoa carambola L.）的叶中分离得到 10 种未被描述的二氢查尔酮 C-糖苷，即杨桃苷 R1‒R3、S1、S2、T1‒T3、3-羟基杨桃苷 T1 和 3-羟基杨桃苷 P。通过光谱和化学方法确定了它们的结构。其中，杨桃苷 P、T1、T2 和 I 的含量分别为 22.78、14.39、4.93 和 1.87 mg g 干重，通过 HPLC 分析表明它们在叶中含量丰富。所有化合物均表现出比 l-抗坏血酸更强的 ABTS 自由基清除活性。3-羟基杨桃苷 T1 和 3-羟基杨桃苷 P 还表现出中等的 DPPH 自由基清除活性。此外，杨桃苷 R3、3-羟基杨桃苷 T1 和 3-羟基杨桃苷 P 表现出较弱的体外猪胰腺脂肪酶抑制活性。
