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加拿大的药物不良反应(2009 - 2018年):来自加拿大药物警戒数据库的见解

Adverse Drug Reactions in Canada (2009-2018): Insights from the Canada Vigilance Database.

作者信息

Maity Tuhin S, Longo Christopher J

机构信息

currently a doctoral student at the DeGroote School of Business, McMaster University. Tuhin has previously earned a doctoral degree in chemistry and held various research positions. He can be reached at

An associate professor in health policy and management at DeGroote School of Business, McMaster University. Christopher has over 20 years of industry experience in clinical research, economic evaluation and market access strategies for pharmaceuticals.

出版信息

Healthc Q. 2020 Apr;23(1):40-46. doi: 10.12927/hcq.2020.26140.

DOI:10.12927/hcq.2020.26140
PMID:32249738
Abstract

Annually, thousands of individuals die and tens of thousands are hospitalized in association with suspected adverse drug reactions (ADRs) in Canada. We analyzed the reports from the Canada Vigilance Adverse Reaction online database and present a synopsis of the state of ADRs in Canada between 2009 and 2018. Our synopsis includes both cross-sectional and longitudinal insights into ADR demographics, outcomes, associated drugs and disease indications. In closing, we highlight five overarching issues uncovered in our analysis, which have potential implications for future policy formulation. Further in-depth exploration is required to shine some additional light on these issues.

摘要

在加拿大,每年都有成千上万的人因疑似药物不良反应(ADR)死亡,还有数万人住院。我们分析了加拿大药物警戒不良反应在线数据库的报告,并概述了2009年至2018年期间加拿大药物不良反应的状况。我们的概述包括对药物不良反应的人口统计学、结果、相关药物和疾病适应症的横断面和纵向见解。最后,我们强调了分析中发现的五个总体问题,这些问题可能对未来的政策制定产生影响。需要进一步深入探讨,以更清楚地了解这些问题。

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