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大鼠附睾和输精管的淋巴引流及其与输精管切除免疫反应的关系。

The lymphatic drainage of the epididymis and of the ductus deferens of the rat, with reference to the immune response to vasectomy.

作者信息

McDonald S W, Scothorne R J

机构信息

Department of Anatomy, University of Glasgow, Scotland.

出版信息

J Anat. 1988 Jun;158:57-64.

Abstract

The lymphatic drainage of the testis, epididymis and ductus deferens was determined in unoperated and in unilaterally vasectomised Albino Swiss rats. In the vasectomised animals, the lymphatic drainage of epididymal and vasal sperm granulomas was also investigated. The normal epididymis, and sperm granulomas which develop in it after vasectomy, drain to the regional testicular lymph node via the inferior epididymal trunk; vasectomy does not interfere with this route. There is a lymphatic watershed within the middle one third of the scrotal ductus deferens; lymph may drain caudally, to enter the inferior epididymal trunk and/or rostrally to the iliac node. Lymphatics draining granulomas at the vasectomy site, may, therefore, be interrupted by vasectomy. This would contribute to, but does not fully explain, the variable immune response of the regional testicular node following vasectomy.

摘要

在未手术和单侧输精管结扎的白化瑞士大鼠中,确定了睾丸、附睾和输精管的淋巴引流情况。在输精管结扎的动物中,还研究了附睾和输精管精子肉芽肿的淋巴引流。正常附睾以及输精管结扎后在其中形成的精子肉芽肿,通过附睾下干引流至区域睾丸淋巴结;输精管结扎并不干扰这一途径。在阴囊段输精管的中三分之一处存在一个淋巴分水岭;淋巴可向尾侧引流,进入附睾下干,和/或向头侧引流至髂淋巴结。因此,输精管结扎可能会中断输精管结扎部位肉芽肿的淋巴管引流。这可能会导致输精管结扎后区域睾丸淋巴结的免疫反应多变,但不能完全解释这种现象。

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